EP 3334411 A1 20180620 - INJECTABLE LIQUID COMPOSITION FOR USE IN THE INTRA-ARTICULAR INFILTRATION THERAPY
Title (en)
INJECTABLE LIQUID COMPOSITION FOR USE IN THE INTRA-ARTICULAR INFILTRATION THERAPY
Title (de)
INJIZIERBARE FLÜSSIGE ZUSAMMENSETZUNG ZUR VERWENDUNG IN DER INTRAARTIKULÄREN INFILTRATIONSTHERAPIE
Title (fr)
COMPOSITION LIQUIDE INJECTABLE POUR UTILISATION DANS LA THÉRAPIE PAR INFILTRATION INTRA-ARTICULAIRE
Publication
Application
Priority
- IT UB20153110 A 20150813
- IB 2016054809 W 20160810
Abstract (en)
[origin: WO2017025903A1] The present invention relates to an injectable liquid composition comprising an effective amount of a mixture which comprises or, alternatively, consists of hyaluronic acid (and/or a pharmaceutically acceptable salt thereof) and methylsulfonylmethane, and a physiologically acceptable carrier; said composition being for use in the intra-articular infiltration therapy, wherein said hyaluronic acid, or a pharmaceutically acceptable salt thereof, has an average molecular weight comprised from 800 KDa to 1200 KDa, preferably 1000 KDa, and the methylsulfonylmethane is in an amount by weight comprised from 0.5% to 8%, preferably from 1 % to 5%, relative to the total weight of the composition. In particular, the present invention relates to said injectable liquid composition for use in the treatment of osteoarthritis of the knee.
IPC 8 full level
A61K 9/00 (2006.01); A61K 31/10 (2006.01); A61K 31/728 (2006.01); A61P 19/02 (2006.01)
CPC (source: EP)
A61K 9/0019 (2013.01); A61K 31/10 (2013.01); A61K 31/728 (2013.01); A61K 47/02 (2013.01); A61P 19/02 (2017.12)
Citation (search report)
See references of WO 2017025903A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2017025903 A1 20170216; EP 3334411 A1 20180620; EP 3334411 B1 20210929; HK 1255848 A1 20190830; HU E056353 T2 20220228; IT UB20153110 A1 20170213
DOCDB simple family (application)
IB 2016054809 W 20160810; EP 16767361 A 20160810; HK 18114924 A 20181122; HU E16767361 A 20160810; IT UB20153110 A 20150813