EP 3337459 A1 20180627 - SALTS OF ACTIVE INGREDIENTS WITH POLYMERIC COUNTERIONS
Title (en)
SALTS OF ACTIVE INGREDIENTS WITH POLYMERIC COUNTERIONS
Title (de)
SALZE VON WIRKSTOFFEN MIT POLYMEREN GEGENIONEN
Title (fr)
SELS DE PRINCIPES ACTIFS AYANT DES CONTRE-IONS POLYMÈRES
Publication
Application
Priority
- EP 15181991 A 20150821
- EP 2016069457 W 20160817
Abstract (en)
[origin: WO2017032651A1] The invention relates to water-soluble polymeric salts of poorly water-soluble medicaments, consisting of a cationogenic medicament which has in an uncharged form or as a hydrochloride a solubility of less than 0.1 % (m/m) in water, artificial intestinal juice or gastric juice, and consisting of an anionogenic water-soluble polymer which has a water solubility of at least 5 % (m/m) in the pH range of 1 to 13 and is obtained by a radically initiated polymerization of a monomer mixture consisting of i) 70 to 90 wt.% of n-vinylpyrrolidone and ii) 10 to 30 wt.% of acrylic acid, the sum of i) and ii) corresponding to 100 wt.%.
IPC 8 full level
A61K 9/16 (2006.01); A61K 31/00 (2006.01); C08F 220/06 (2006.01)
CPC (source: EP US)
A61K 9/1635 (2013.01 - EP US); A61K 9/2027 (2013.01 - EP US); A61K 31/00 (2013.01 - US); A61K 31/426 (2013.01 - EP US); A61K 31/451 (2013.01 - EP US); A61K 31/4515 (2013.01 - EP US); A61K 31/495 (2013.01 - EP US); A61K 47/6933 (2017.07 - US); C08F 220/06 (2013.01 - EP US); C08F 226/10 (2013.01 - EP US); C08L 33/08 (2013.01 - US); C08L 39/06 (2013.01 - US); C08L 2203/02 (2013.01 - US)
Citation (search report)
See references of WO 2017032651A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2017032651 A1 20170302; CN 107921000 A 20180417; CN 107921000 B 20210330; EP 3337459 A1 20180627; JP 2018523692 A 20180823; JP 6914917 B2 20210804; US 10610487 B2 20200407; US 2018235885 A1 20180823
DOCDB simple family (application)
EP 2016069457 W 20160817; CN 201680048050 A 20160817; EP 16757598 A 20160817; JP 2018509497 A 20160817; US 201615753186 A 20160817