EP 3338804 A1 20180627 - ENTERIC CAPSULE
Title (en)
ENTERIC CAPSULE
Title (de)
ENTERALE KAPSEL
Title (fr)
CAPSULE ENTÉRIQUE
Publication
Application
Priority
- JP 2015161910 A 20150819
- JP 2016073617 W 20160810
Abstract (en)
Provided is a capsule excellent in enteric property with the assumption that gelatin is used as a main base material of the capsule coating. An alkali-treated gelatin and carrageenan are contained as base materials of the capsule coating. In the gastric (aqueous) environment, the alkali-treated gelatin which is positively (+) charged coexists with the carrageenan which is negatively (-) charged, and amino groups (NH4+) in the gelatin react with sulfate groups (SO3-) in the carrageenan so that the capsule coating is insolubilized. On the other hand, in the intestinal (aqueous) environment, the alkali-treated gelatin which is negatively (-) charged coexists with the carrageenan which is negatively (-) charged, and the amino groups (NH4+) in the gelatin are repulsive to the sulfate groups (SO3-) in the carrageenan so that the capsule coating quickly disintegrates and dissolves.
IPC 8 full level
A61K 47/36 (2006.01); A61K 8/11 (2006.01); A61K 8/64 (2006.01); A61K 8/73 (2006.01); A61K 9/48 (2006.01); A61K 47/42 (2017.01)
CPC (source: EP KR US)
A61K 8/11 (2013.01 - KR US); A61K 8/64 (2013.01 - KR US); A61K 8/73 (2013.01 - KR US); A61K 9/48 (2013.01 - US); A61K 9/4808 (2013.01 - US); A61K 9/4825 (2013.01 - EP KR US); A61K 9/4891 (2013.01 - US); A61K 47/36 (2013.01 - KR US); A61K 47/42 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 3338804 A1 20180627; EP 3338804 A4 20190501; EP 3338804 B1 20200429; CN 107921142 A 20180417; CN 107921142 B 20201201; DK 3338804 T3 20200602; JP 2017039657 A 20170223; JP 5878669 B1 20160308; KR 102519593 B1 20230407; KR 20180040139 A 20180419; PH 12018500228 A1 20180813; PH 12018500228 B1 20180813; SG 11201800516T A 20180227; US 10493036 B2 20191203; US 2018221288 A1 20180809; WO 2017030072 A1 20170223
DOCDB simple family (application)
EP 16837062 A 20160810; CN 201680046664 A 20160810; DK 16837062 T 20160810; JP 2015161910 A 20150819; JP 2016073617 W 20160810; KR 20187003864 A 20160810; PH 12018500228 A 20180129; SG 11201800516T A 20160810; US 201615748140 A 20160810