EP 3345003 A1 20180711 - IDENTIFICATION OF PROTEINS IN THE ABSENCE OF PEPTIDE IDENTIFICATIONS
Title (en)
IDENTIFICATION OF PROTEINS IN THE ABSENCE OF PEPTIDE IDENTIFICATIONS
Title (de)
IDENTIFIZIERUNG VON PROTEINEN IN ABWESENHEIT VON PEPTIDIDENTIFIZIERUNGEN
Title (fr)
IDENTIFICATION DE PROTÉINES EN L'ABSENCE D'IDENTIFICATIONS DE PEPTIDES
Publication
Application
Priority
- US 201562212282 P 20150831
- IB 2016054990 W 20160819
Abstract (en)
[origin: WO2017037563A1] A plurality of measured product ion spectra are produced using a DIA tandem mass spectrometry method for a sample of two or more known proteins. A desired confidence probability for the identification of at least one known protein of two or more known proteins is received. Two or more combinations of N theoretical product ions that are exclusive to the at least one known protein are calculated. The at least one known protein is identified by finding product ions in the plurality of measured product ion spectra that match two or more of the two or more combinations of N theoretical product ions that provide a combined confidence probability greater than or equal to the desired confidence probability.
IPC 8 full level
G01N 33/68 (2006.01); G06F 19/10 (2011.01); G06F 19/18 (2011.01); G16B 40/10 (2019.01); H01J 49/00 (2006.01)
CPC (source: EP US)
G01N 33/6848 (2013.01 - EP); G16B 40/00 (2019.01 - EP); G16B 40/10 (2019.01 - EP US); H01J 49/0036 (2013.01 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2017037563 A1 20170309; EP 3345003 A1 20180711; EP 3345003 A4 20190515
DOCDB simple family (application)
IB 2016054990 W 20160819; EP 16840911 A 20160819