EP 3349775 B1 20211201 - SOLID PHASE PEPTIDE SYNTHESIS METHODS AND ASSOCIATED SYSTEMS
Title (en)
SOLID PHASE PEPTIDE SYNTHESIS METHODS AND ASSOCIATED SYSTEMS
Title (de)
FESTPHASEN-PEPTIDSYNTHESEVERFAHREN UND ZUGEHÖRIGE SYSTEME
Title (fr)
PROCÉDÉS DE SYNTHÈSE DE PEPTIDES EN PHASE SOLIDE ET SYSTÈMES ASSOCIÉS
Publication
Application
Priority
- US 201562220232 P 20150917
- US 2016052179 W 20160916
Abstract (en)
[origin: US2017081359A1] Methods and system for solid phase peptide synthesis are provided. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. New amino acid residues are added via a coupling reaction between an activated amino acid and an amino acid residue of the immobilized peptide. Amino acids may be activated using, e.g., a base and an activating agent. Certain inventive concepts, described herein, relate to methods and systems for the activation of amino acids. These systems and methods may allow for fewer side reactions and a higher yield compared to conventional activation techniques as well as the customization of the coupling reaction on a residue-by-residue basis without the need for costly and/or complex processes.
IPC 8 full level
C07K 1/04 (2006.01)
CPC (source: EP US)
B01J 19/24 (2013.01 - US); C07K 1/045 (2013.01 - EP US); C07K 1/084 (2013.01 - US); C07K 7/06 (2013.01 - US); C07K 14/47 (2013.01 - US); C07K 14/60 (2013.01 - EP US); C07K 14/61 (2013.01 - US); C07K 14/62 (2013.01 - EP US); B01J 2219/24 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 2017081359 A1 20170323; CA 2999027 A1 20170323; CN 108289925 A 20180717; DK 3349775 T3 20220307; EP 3349775 A1 20180725; EP 3349775 A4 20190515; EP 3349775 B1 20211201; EP 3960753 A1 20220302; JP 2018528965 A 20181004; JP 7054922 B2 20220415; US 2021188901 A1 20210624; US 2023174572 A1 20230608; WO 2017049115 A1 20170323
DOCDB simple family (application)
US 201615267995 A 20160916; CA 2999027 A 20160916; CN 201680066697 A 20160916; DK 16847410 T 20160916; EP 16847410 A 20160916; EP 21203130 A 20160916; JP 2018514421 A 20160916; US 2016052179 W 20160916; US 202017086196 A 20201030; US 202217747952 A 20220518