EP 3350164 A4 20190327 - FARNESOID X RECEPTOR AGONISTS AND USES THEREOF
Title (en)
FARNESOID X RECEPTOR AGONISTS AND USES THEREOF
Title (de)
FARNESOID-X-REZEPTORAGONISTEN UND VERWENDUNGEN DAVON
Title (fr)
AGONISTES DU RÉCEPTEUR X FARNÉSOÏDE ET LEURS UTILISATIONS
Publication
Application
Priority
- US 201562219427 P 20150916
- US 201662333560 P 20160509
- US 2016052274 W 20160916
Abstract (en)
[origin: WO2017049176A1] Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
IPC 8 full level
A61K 31/4418 (2006.01); A61K 31/4465 (2006.01); C07C 233/55 (2006.01); C07C 233/63 (2006.01); C07D 211/10 (2006.01); C07D 213/04 (2006.01); C07D 213/06 (2006.01)
CPC (source: EP US)
A61K 31/196 (2013.01 - EP US); A61K 31/216 (2013.01 - EP US); A61K 31/397 (2013.01 - EP US); A61K 31/402 (2013.01 - EP US); A61K 31/4418 (2013.01 - EP US); A61K 31/451 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 1/16 (2017.12 - EP US); C07C 233/54 (2013.01 - EP US); C07C 233/63 (2013.01 - EP US); C07C 235/40 (2013.01 - EP US); C07D 205/04 (2013.01 - EP US); C07D 207/09 (2013.01 - EP US); C07D 211/26 (2013.01 - EP US); C07D 213/40 (2013.01 - EP US); C07C 2601/14 (2017.04 - EP US)
Citation (search report)
- [A] US 4259352 A 19810331 - SHEPHERD ROBERT G
- [A] RICHTER HANS G F ET AL: "Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, no. 1, 12 November 2010 (2010-11-12), pages 191 - 194, XP029121288, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2010.11.039
- [A] K. C. NICOLAOU ET AL: "Discovery and Optimization of Non-steroidal FXR Agonists from Natural Product-Like Libraries.", CHEMINFORM, vol. 34, no. 24, 17 June 2003 (2003-06-17), DE, XP055553984, ISSN: 0931-7597, DOI: 10.1002/chin.200324210
- See references of WO 2017049176A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2017049176 A1 20170323; EP 3350164 A1 20180725; EP 3350164 A4 20190327; JP 2018536016 A 20181206; US 2019062277 A1 20190228
DOCDB simple family (application)
US 2016052274 W 20160916; EP 16847455 A 20160916; JP 2018534464 A 20160916; US 201615758710 A 20160916