EP 3359259 A4 20190424 - RESETTING BIOLOGICAL PATHWAYS FOR DEFENDING AGAINST AND REPAIRING DETERIORATION FROM HUMAN AGING
Title (en)
RESETTING BIOLOGICAL PATHWAYS FOR DEFENDING AGAINST AND REPAIRING DETERIORATION FROM HUMAN AGING
Title (de)
ZURÜCKSETZEN BIOLOGISCHER WEGE ZUR ABWEHR UND BEHEBUNG VON ALTERUNGSERSCHEINUNGEN BEIM MENSCHEN
Title (fr)
RÉINITIALISATION DE VOIES BIOLOGIQUES DE DÉFENSE CONTRE ET DE RÉPARATION D'UNE DÉTÉRIORATION CAUSÉE PAR LE VIEILLISSEMENT HUMAIN
Publication
Application
Priority
- US 201562238338 P 20151007
- US 2016055173 W 20161003
Abstract (en)
[origin: WO2017062311A1] Compositions for addressing one or more of the effects of aging are described. The compositions comprise a first component comprising repair system activator(s) such as nicotinamide adenine dinucleotide (NAD+), nicotinamide mononucleotide (NMN), nicotinamide riboside (NR), nicotinic acid adenine mononucleotide (NaMN), nicotinic acid adenine dinucleotide (NaAD), nicotinic acid riboside (NAR), 1-methylnicotinamide (MNM), cyclic adenosine monophosphate (cAMP) and combinations thereof; a second component comprising methyl donor(s) such as S-5'-adenosyl-L-methionine (SAM), methionine, betaine, choline, folate, vitamin B12, or combinations thereof; and a third component comprising antioxidant defense activators such as H2O2, N2S, NaSH, Na2S, and several others, including combinations thereof. Methods of administering the disclosed compositions or separate formulations of repair system activator, methyl donors, and antioxidant defense activators are also disclosed.
IPC 8 full level
A61P 39/00 (2006.01); A23L 33/13 (2016.01); A23L 33/175 (2016.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 31/045 (2006.01); A61K 31/198 (2006.01); A61K 31/205 (2006.01); A61K 31/706 (2006.01); A61K 31/714 (2006.01); A61K 33/04 (2006.01); A61K 33/40 (2006.01); A61K 36/258 (2006.01); A61K 36/48 (2006.01); A61P 29/00 (2006.01); A61P 37/04 (2006.01)
CPC (source: EP IL KR RU US)
A23L 33/13 (2016.08 - EP IL KR US); A23L 33/175 (2016.08 - EP IL KR US); A61K 9/00 (2013.01 - RU); A61K 9/0019 (2013.01 - IL KR US); A61K 9/0095 (2013.01 - IL US); A61K 9/20 (2013.01 - IL KR RU US); A61K 31/045 (2013.01 - EP IL US); A61K 31/198 (2013.01 - EP IL RU US); A61K 31/205 (2013.01 - EP IL RU US); A61K 31/706 (2013.01 - EP IL KR RU US); A61K 31/7084 (2013.01 - KR RU); A61K 31/714 (2013.01 - EP IL US); A61K 33/00 (2013.01 - RU); A61K 33/04 (2013.01 - EP IL RU US); A61K 33/40 (2013.01 - EP IL RU US); A61K 36/258 (2013.01 - EP IL US); A61K 36/48 (2013.01 - RU); A61P 29/00 (2018.01 - EP IL RU US); A61P 37/04 (2018.01 - EP IL US); A61P 39/00 (2018.01 - KR RU); A61P 43/00 (2018.01 - RU); A23V 2002/00 (2013.01 - EP IL KR US); A23V 2200/302 (2013.01 - IL KR); A61K 2300/00 (2013.01 - IL)
C-Set (source: EP US)
Citation (search report)
- [E] WO 2016158212 A1 20161006 - SHINKOWA PHARMACEUTICAL CO LTD [JP], et al
- [IY] SUE DUNLEVY: "University of NSW research finds compound that can reverse ageing", NEWS.COM.AU/LIFESTYLE/HEALTH, 19 December 2013 (2013-12-19), Internet, pages 1 - 2, XP055570000, Retrieved from the Internet <URL:https://www.news.com.au/lifestyle/health/university-of-nsw-research-finds-compound-that-can-reverse-ageing/news-story/2db52e293fb786faf08acf57da7d0bb7> [retrieved on 20190315]
- [Y] MARIA GIULIA BACALINI ET AL: "Present and future of anti-ageing epigenetic diets", MECHANISMS OF AGEING AND DEVELOPMENT., vol. 136-137, 1 March 2014 (2014-03-01), CH, pages 101 - 115, XP055570022, ISSN: 0047-6374, DOI: 10.1016/j.mad.2013.12.006
- [Y] E. K. GO ET AL: "Betaine Suppresses Proinflammatory Signaling During Aging: The Involvement of Nuclear Factor- B via Nuclear Factor-Inducing Kinase/I B Kinase and Mitogen-Activated Protein Kinases", JOURNALS OF GERONTOLOGY, SERIES A, BIOLOGICAL SCIENCES ANDMEDICAL SCIENCES, vol. 60, no. 10, 1 October 2005 (2005-10-01), US, pages 1252 - 1264, XP055570016, ISSN: 1079-5006, DOI: 10.1093/gerona/60.10.1252
- [Y] ALARCON DE LA LASTRA CATALINA ET AL: "RESVERATROL AS AN ANTI-INFLAMMATORY AND ANTI-AGING AGENT: MECHANISMS AND CLINICAL IMPLICATIONS", MOLECULAR NUTRITION & FOOD RESEARCH, WILEY - VCH VERLAG, WEINHEIM, DE, vol. 49, no. 5, 1 May 2005 (2005-05-01), pages 405 - 430, XP009077313, ISSN: 1613-4125, DOI: 10.1002/MNFR.200500022
- See also references of WO 2017062311A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2017062311 A1 20170413; AU 2016335968 A1 20180510; AU 2016335968 B2 20221027; AU 2023200040 A1 20230209; BR 112018007153 A2 20181106; CA 3001483 A1 20170413; CA 3118834 A1 20170413; CA 3118834 C 20240611; CN 108290059 A 20180717; EP 3359259 A1 20180815; EP 3359259 A4 20190424; EP 3359259 B1 20231115; EP 3359259 C0 20231115; HK 1258406 A1 20191108; IL 258541 A 20180531; IL 258541 B 20220501; IL 292414 A 20220601; IL 292414 B2 20230601; IL 299824 A 20230301; IL 299824 B1 20231001; IL 299824 B2 20240201; JP 2018530614 A 20181018; JP 2022122921 A 20220823; JP 7515235 B2 20240712; KR 20180063179 A 20180611; MX 2018004358 A 20180523; MX 2022013626 A 20221116; RU 2018114520 A 20191107; RU 2018114520 A3 20200221; RU 2768936 C2 20220325; SG 11201802933Y A 20180530; US 2019060336 A1 20190228; US 2022023323 A1 20220127
DOCDB simple family (application)
US 2016055173 W 20161003; AU 2016335968 A 20161003; AU 2023200040 A 20230104; BR 112018007153 A 20161003; CA 3001483 A 20161003; CA 3118834 A 20161003; CN 201680071250 A 20161003; EP 16854140 A 20161003; HK 19100813 A 20190117; IL 25854118 A 20180408; IL 29241422 A 20220424; IL 29982423 A 20230111; JP 2018538047 A 20161003; JP 2022084999 A 20220525; KR 20187011865 A 20161003; MX 2018004358 A 20161003; MX 2022013626 A 20180409; RU 2018114520 A 20161003; SG 11201802933Y A 20161003; US 201615766990 A 20161003; US 202117376621 A 20210715