EP 3366701 B1 20190703 - COMPOSITIONS AND METHODS FOR THE ALTERATION OF XLHED PHENOTYPES
Title (en)
COMPOSITIONS AND METHODS FOR THE ALTERATION OF XLHED PHENOTYPES
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR VERÄNDERUNG VON XLHED-PHÄNOTYPEN
Title (fr)
COMPOSITIONS ET PROCÉDÉS DE MODIFICATION DE PHÉNOTYPES XLHED
Publication
Application
Priority
- US 201161485677 P 20110513
- EP 16199966 A 20120510
- EP 12785709 A 20120510
- US 2012037251 W 20120510
Abstract (en)
[origin: WO2012158445A1] The invention relates to methods for the temporal administration of EDA agonists, in particular EDI200, which correlate to optimal therapeutic response windows required for the formation of any EDA-dependent structures such as ectodermal appendages. Use of the methods described allow for the design of targeted therapeutic dosing and administration regimens in order to correct or alter abnormal phenotypes associated with genetic disorders, in particular, XLHED.
IPC 8 full level
C07K 16/00 (2006.01); A61K 9/00 (2006.01); A61K 38/17 (2006.01); A61K 39/00 (2006.01); A61K 47/68 (2017.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 16/28 (2006.01); C07K 17/00 (2006.01); C07K 17/14 (2006.01); C12P 21/08 (2006.01)
CPC (source: CN EP KR US)
A61K 9/0019 (2013.01 - CN US); A61K 38/179 (2013.01 - CN EP US); A61K 39/395 (2013.01 - KR); A61K 47/6811 (2017.08 - EP US); A61P 1/02 (2018.01 - EP); A61P 11/04 (2018.01 - EP); A61P 17/00 (2018.01 - EP); A61P 17/14 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 14/47 (2013.01 - EP US); C07K 14/70575 (2013.01 - US); C07K 14/70578 (2013.01 - US); C07K 14/7151 (2013.01 - EP US); C07K 16/18 (2013.01 - KR); C07K 16/2866 (2013.01 - EP US); C07K 19/00 (2013.01 - KR); A61K 2039/505 (2013.01 - EP US); C07K 2317/24 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US); C07K 2319/30 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012158445 A1 20121122; AU 2012256174 A1 20131031; AU 2012256174 A2 20140109; AU 2012256174 B2 20161027; BR 112013029331 A2 20171219; BR 112013029331 B1 20211116; CA 2835882 A1 20121122; CA 2835882 C 20190917; CN 103534269 A 20140122; CN 103534269 B 20160525; CN 105999225 A 20161012; CN 105999225 B 20191224; EP 2697258 A1 20140219; EP 2697258 A4 20141112; EP 2697258 B1 20170201; EP 3159356 A1 20170426; EP 3159356 B1 20180815; EP 3366701 A1 20180829; EP 3366701 B1 20190703; HK 1254904 B 20200417; IL 229015 A0 20131231; JP 2014519495 A 20140814; JP 2016185974 A 20161027; JP 5955382 B2 20160720; JP 6190921 B2 20170830; KR 20140043380 A 20140409; MX 2013013235 A 20140108; NZ 616824 A 20151224; RU 2013155476 A 20150620; SG 194539 A1 20131230; US 10426819 B2 20191001; US 2015017161 A1 20150115; US 2016184393 A1 20160630; US 2018169188 A1 20180621; US 9175085 B2 20151103; US 9925239 B2 20180327; ZA 201407978 B 20160525
DOCDB simple family (application)
US 2012037251 W 20120510; AU 2012256174 A 20120510; BR 112013029331 A 20120510; CA 2835882 A 20120510; CN 201280023625 A 20120510; CN 201610318819 A 20120510; EP 12785709 A 20120510; EP 16199966 A 20120510; EP 18168198 A 20120510; HK 18114003 A 20181102; IL 22901513 A 20131022; JP 2014510458 A 20120510; JP 2016117831 A 20160614; KR 20137032686 A 20120510; MX 2013013235 A 20120510; NZ 61682412 A 20120510; RU 2013155476 A 20120510; SG 2013077748 A 20120510; US 201214117431 A 20120510; US 201514861292 A 20150922; US 201815890431 A 20180207; ZA 201407978 A 20141031