EP 3370773 B1 20220105 - COMBINATION THERAPY OF IMMUNOTOXIN AND CHECKPOINT INHIBITOR
Title (en)
COMBINATION THERAPY OF IMMUNOTOXIN AND CHECKPOINT INHIBITOR
Title (de)
KOMBINATIONSTHERAPIE MIT IMMUNTOXIN UND CHECKPOINT-INHIBITOR
Title (fr)
POLYTHÉRAPIE CONSTITUÉE D'IMMUNOTOXINES ET D'UN INHIBITEUR DE POINT DE CONTRÔLE
Publication
Application
Priority
- US 201562250749 P 20151104
- US 2016060469 W 20161104
Abstract (en)
[origin: WO2017079520A1] Regional, tumor-targeted, cytotoxic therapy, such as D2C7-immunotoxin (D2C7-IT), not only specifically target and destroy tumor cells, but in the process initiate immune events that promote an in situ vaccine effect. The antitumor effects are amplified by immune checkpoint blockade which engenders a long-term systemic immune response that effectively eliminates all tumor cells.
IPC 8 full level
A61K 39/395 (2006.01); A61K 31/00 (2006.01); A61K 38/16 (2006.01); A61K 39/00 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01)
CPC (source: CN EP US)
A61K 38/164 (2013.01 - EP US); A61K 39/395 (2013.01 - EP US); A61K 39/3955 (2013.01 - CN EP US); A61K 45/06 (2013.01 - CN); A61K 47/6829 (2017.08 - EP US); A61K 47/6849 (2017.08 - EP US); A61K 47/6851 (2017.08 - EP US); A61P 35/00 (2018.01 - CN EP US); C07K 16/2818 (2013.01 - EP US); C07K 16/2863 (2013.01 - EP US); C07K 16/30 (2013.01 - EP US); A61K 2039/505 (2013.01 - EP US); A61K 2039/507 (2013.01 - EP US); C07K 2317/622 (2013.01 - US); C07K 2317/624 (2013.01 - EP US); C07K 2317/73 (2013.01 - EP US); C07K 2317/76 (2013.01 - EP US); C07K 2319/55 (2013.01 - EP US)
C-Set (source: CN EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2017079520 A1 20170511; CN 108367070 A 20180803; CN 108367070 B 20221028; CN 116327955 A 20230627; EP 3370773 A1 20180912; EP 3370773 A4 20190529; EP 3370773 B1 20220105; EP 3973988 A1 20220330; JP 2018533626 A 20181115; JP 6587756 B2 20191009; US 11065332 B2 20210720; US 2018311346 A1 20181101; US 2021338811 A1 20211104; US 2024350624 A1 20241024
DOCDB simple family (application)
US 2016060469 W 20161104; CN 201680070875 A 20161104; CN 202211240353 A 20161104; EP 16863025 A 20161104; EP 21193555 A 20161104; JP 2018543049 A 20161104; US 201615773418 A 20161104; US 202117376319 A 20210715; US 202418428597 A 20240131