EP 3370868 A1 20180912 - MICROFLUIDIC ELECTROWETTING DEVICE APPARATUS HAVING A COVALENTLY BOUND HYDROPHOBIC SURFACE
Title (en)
MICROFLUIDIC ELECTROWETTING DEVICE APPARATUS HAVING A COVALENTLY BOUND HYDROPHOBIC SURFACE
Title (de)
MIKROFLUIDISCHE ELEKTROBENETZUNGSVORRICHTUNG MIT EINER KOVALENT GEBUNDENEN HYDROPHOBEN OBERFLÄCHE
Title (fr)
APPAREIL MICROFLUIDIQUE COMPRENANT UN DISPOSITIF D'ÉLECTROMOUILLAGE AYANT UNE SURFACE HYDROPHOBE LIÉE PAR COVALENCE
Publication
Application
Priority
- US 201562246605 P 20151027
- US 201562247725 P 20151028
- US 201615135707 A 20160422
- US 201662342131 P 20160526
- US 201662410238 P 20161019
- US 2016059234 W 20161027
Abstract (en)
[origin: WO2017075295A1] Microfluidic devices having an electrowetting configuration and an optimized droplet actuation surface are provided. The devices include a conductive substrate having a dielectric layer, a hydrophobic layer covalently bonded to the dielectric layer, and a first electrode electrically coupled to the dielectric layer and configured to be connected to a voltage source. The microfluidic devices also include a second electrode, optionally included in a cover, configured to be connected to the voltage source. The hydrophobic layer features self-associating molecules covalently bonded to a surface of the dielectric layer in a manner that produces a densely-packed monolayer that resists intercalation and or penetration by polar molecules or species. Also provided are microfluidic devices having an electrowetting configuration that further include a section or module having a dielectrophoresis configuration; systems that include any of the microfluidic devices in combination with an aqueous droplet and a fluidic medium immiscible with the medium of the aqueous droplet; related kits; and methods of manipulating droplets, optionally containing micro-objects such as biological cells, within the microfluidic devices.
IPC 8 full level
B01L 3/00 (2006.01)
CPC (source: EP IL KR)
B01L 3/502707 (2013.01 - EP IL KR); B01L 3/50273 (2013.01 - EP IL KR); B01L 3/502784 (2013.01 - EP IL KR); B01L 3/502792 (2013.01 - IL KR); B01L 3/502792 (2013.01 - EP); B01L 2200/0605 (2013.01 - EP IL KR); B01L 2200/0668 (2013.01 - EP IL); B01L 2200/0673 (2013.01 - EP IL KR); B01L 2300/0816 (2013.01 - EP IL KR); B01L 2300/0864 (2013.01 - EP IL KR); B01L 2300/165 (2013.01 - EP IL KR); B01L 2400/0424 (2013.01 - EP IL KR); B01L 2400/0427 (2013.01 - EP IL KR)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2017075295 A1 20170504; WO 2017075295 A8 20180531; AU 2016344171 A1 20180510; AU 2016344171 B2 20210923; AU 2021286430 A1 20220120; CA 3001616 A1 20170504; CA 3001616 C 20230905; CN 108472649 A 20180831; CN 108472649 B 20220114; CN 114289087 A 20220408; CN 114289087 B 20240326; EP 3370868 A1 20180912; EP 3370868 B1 20201209; EP 3862088 A1 20210811; IL 258851 A 20180628; IL 258851 B1 20230401; IL 258851 B2 20230801; JP 2018535088 A 20181129; JP 2021126656 A 20210902; JP 6891169 B2 20210618; KR 102426825 B1 20220728; KR 20180072812 A 20180629; SG 10202107069U A 20210729; SG 11201802968V A 20180530; TW 201726540 A 20170801; TW 202126571 A 20210716; TW I714656 B 20210101; TW I781484 B 20221021
DOCDB simple family (application)
US 2016059234 W 20161027; AU 2016344171 A 20161027; AU 2021286430 A 20211217; CA 3001616 A 20161027; CN 201680077445 A 20161027; CN 202210023074 A 20161027; EP 16794477 A 20161027; EP 20211621 A 20161027; IL 25885118 A 20180422; JP 2018519385 A 20161027; JP 2021088097 A 20210526; KR 20187014919 A 20161027; SG 10202107069U A 20161027; SG 11201802968V A 20161027; TW 105134881 A 20161027; TW 109142086 A 20161027