EP 3371185 B1 20200930 - 4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE AND 1,4,5,6,7,8-HEXAHYDROIMIDAZO[4,5-D]AZEPINE DERIVATIVES AS JANUS KINASE INHIBITORS
Title (en)
4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE AND 1,4,5,6,7,8-HEXAHYDROIMIDAZO[4,5-D]AZEPINE DERIVATIVES AS JANUS KINASE INHIBITORS
Title (de)
4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDIN- UND 1,4,5,6,7,8-HEXAHYDROIMIDAZO[4,5-D]AZEPIN-DERIVATE ALS JANUS-KINASE-INHIBITOREN
Title (fr)
DÉRIVÉS DE 4,5,6,7-TÉTRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE ET 1,4,5,6,7,8-HEXAHYDROIMIDAZO[4,5-D]AZÉPINE À UTILISER EN TANT QU'INHIBITEURS DE JANUS KINASE
Publication
Application
Priority
- GB 201519382 A 20151103
- GB 201606971 A 20160421
- GB 2016053392 W 20161102
Abstract (en)
[origin: WO2017077288A1] There are provided compounds of formula I, wherein X, Ak, s, A, R1 and R2 have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of the JAK family) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
IPC 8 full level
C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/513 (2006.01); A61P 29/00 (2006.01)
CPC (source: EP US)
A61K 45/06 (2013.01 - EP US); A61P 11/06 (2017.12 - EP US); A61P 27/02 (2017.12 - EP US); A61P 29/00 (2017.12 - EP US); C07D 471/04 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2017077288 A1 20170511; CA 3037248 A1 20170511; DK 3371185 T3 20201130; EP 3371185 A1 20180912; EP 3371185 B1 20200930; EP 3831830 A1 20210609; ES 2840650 T3 20210707; PL 3371185 T3 20210406; PT 3371185 T 20201228; US 10556901 B2 20200211; US 10882859 B2 20210105; US 2018370963 A1 20181227; US 2020223843 A1 20200716
DOCDB simple family (application)
GB 2016053392 W 20161102; CA 3037248 A 20161102; DK 16793974 T 20161102; EP 16793974 A 20161102; EP 20199005 A 20161102; ES 16793974 T 20161102; PL 16793974 T 20161102; PT 16793974 T 20161102; US 201615772887 A 20161102; US 201916710074 A 20191211