EP 3373962 A4 20200219 - COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISEASES AND CANCERS
Title (en)
COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISEASES AND CANCERS
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON AUTOIMMUNERKRANKUNGEN UND KREBSERKRANKUNGEN
Title (fr)
COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE MALADIES AUTO-IMMUNES ET DE CANCERS
Publication
Application
Priority
- US 201562253437 P 20151110
- US 2016061086 W 20161109
Abstract (en)
[origin: WO2017083354A1] The present invention provides methods and compositions for treating a cancer, methods for increasing an immune response against a tumor, methods for treating an autoimmune disease, and methods for decreasing an inflammation response in a subject in need thereof by modulating the expression and/or activity of Siglec 15 and/or its binding ligands.
IPC 8 full level
A61K 39/00 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01)
CPC (source: CN EP KR RU US)
A61K 38/00 (2013.01 - RU); A61K 38/005 (2013.01 - EP US); A61K 39/0008 (2013.01 - EP KR US); A61K 39/0011 (2013.01 - KR); A61K 39/395 (2013.01 - KR RU US); A61K 39/3955 (2013.01 - EP US); A61K 39/39566 (2013.01 - US); A61K 45/00 (2013.01 - CN); A61P 25/00 (2018.01 - CN); A61P 29/00 (2018.01 - CN); A61P 35/00 (2018.01 - CN EP KR US); A61P 37/02 (2018.01 - CN EP KR US); A61P 37/04 (2018.01 - CN); C07K 16/2803 (2013.01 - EP KR US); C07K 16/2827 (2013.01 - EP); G01N 33/5008 (2013.01 - US); G01N 33/5011 (2013.01 - EP US); G01N 33/5023 (2013.01 - EP US); G01N 33/57407 (2013.01 - EP US); A61K 2039/505 (2013.01 - EP KR US); C07K 2317/33 (2013.01 - EP); C07K 2317/76 (2013.01 - EP KR US); C07K 2319/30 (2013.01 - EP KR US)
C-Set (source: EP)
Citation (search report)
- [X] WO 2015054600 A2 20150416 - SIAMAB THERAPEUTICS INC [US]
- [I] R. TAKAMIYA ET AL: "The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF- secretion from monocytes/macrophages through the DAP12-Syk pathway", GLYCOBIOLOGY, vol. 23, no. 2, 3 October 2012 (2012-10-03), US, pages 178 - 187, XP055654665, ISSN: 0959-6658, DOI: 10.1093/glycob/cws139
- [X] YUNHE AN ET AL: "A Novel Anti-sTn Monoclonal Antibody 3P9 Inhibits Human Xenografted Colorectal Carcinomas :", JOURNAL OF IMMUNOTHERAPY, vol. 36, no. 1, 1 January 2013 (2013-01-01), US, pages 20 - 28, XP055654675, ISSN: 1524-9557, DOI: 10.1097/CJI.0b013e31827810d1
- [A] JASON E HUDAK ET AL: "Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion -paper", NATURE CHEMICAL BIOLOGY, vol. 10, no. 1, 1 January 2014 (2014-01-01), Basingstoke, pages 69 - 75, XP055619463, ISSN: 1552-4450, DOI: 10.1038/nchembio.1388
- [T] LANYI CHANG ET AL: "Identification of Siglec Ligands Using a Proximity Labeling Method", JOURNAL OF PROTEOME RESEARCH, vol. 16, no. 10, 6 October 2017 (2017-10-06), pages 3929 - 3941, XP055654673, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.7b00625
- [T] WANG JUN ET AL: "Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy", NATURE MEDICINE, NATURE PUB. CO, NEW YORK, vol. 25, no. 4, 4 March 2019 (2019-03-04), pages 656 - 666, XP036749914, ISSN: 1078-8956, [retrieved on 20190304], DOI: 10.1038/S41591-019-0374-X
- See also references of WO 2017083354A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2017083354 A1 20170518; AU 2016354100 A1 20180621; AU 2016354100 B2 20231130; AU 2024201282 A1 20240314; BR 112018009361 A2 20181113; BR 112018009361 A8 20190226; CA 3002095 A1 20170518; CN 108430498 A 20180821; CN 116510015 A 20230801; EP 3373962 A1 20180919; EP 3373962 A4 20200219; HK 1259294 A1 20191129; JP 2018533591 A 20181115; JP 2021167353 A 20211021; JP 2023096078 A 20230706; JP 6924495 B2 20210825; KR 20180073691 A 20180702; MX 2018005830 A 20181112; MX 2023012451 A 20231031; RU 2018121050 A 20191213; RU 2018121050 A3 20200313; RU 2761980 C2 20211214; TW 201729841 A 20170901; TW 202330019 A 20230801; US 2018318419 A1 20181108; US 2022168419 A1 20220602
DOCDB simple family (application)
US 2016061086 W 20161109; AU 2016354100 A 20161109; AU 2024201282 A 20240227; BR 112018009361 A 20161109; CA 3002095 A 20161109; CN 201680065576 A 20161109; CN 202310352979 A 20161109; EP 16864893 A 20161109; HK 19101657 A 20190130; JP 2018523451 A 20161109; JP 2021121460 A 20210726; JP 2023081549 A 20230517; KR 20187015768 A 20161109; MX 2018005830 A 20161109; MX 2023012451 A 20180509; RU 2018121050 A 20161109; TW 105136406 A 20161109; TW 112112070 A 20161109; US 201615775084 A 20161109; US 202217673034 A 20220216