Title (en)

METHOD FOR THE PRODUCTION OF HAIR FOLLICLES AND DE NOVO PAPILLAE, AND USE THEREOF FOR IN VITRO TESTS AND IN VIVO IMPLANTS

Title (de)

VERFAHREN ZUR HERSTELLUNG VON HAARFOLLIKELN UND DE NOVO PAPILLEN SOWIE DEREN VERWENDUNG FÜR IN VITRO TESTS UND IN VIVO IMPLANTATE

Title (fr)

PROCÉDÉ DE PRÉPARATION DE FOLLICULES CAPILLAIRES ET DE PAPILLES DE NOVO, ET LEUR UTILISATION POUR DES TESTS IN VITRO ET DES IMPLANTS IN VIVO

Publication

EP 3377616 A1 20180926 (DE)

Application

EP 16797504 A 20161114

Priority

• DE 102015119880 A 20151117
• EP 2016077541 W 20161114

Abstract (en)

[origin: WO2017084999A1] The invention relates to a method for producing de novo papillae, involving steps a) providing isolated dermal hair papilla fibroblasts (DPF) from at least one dermal papilla (DP) of at least one hair follicle, b) providing isolated connective tissue sheath fibroblasts (CTSF) from at least one hair follicle, and c) co-cultivating the DPF and the CTSF in substantially non-adherent cell culture conditions in order to form spheroidal cell aggregates.

IPC 8 full level

C12N 5/071 (2010.01)

CPC (source: EP US)

A61P 17/14 (2018.01 - EP); C12N 5/0627 (2013.01 - EP US); C12N 5/0698 (2013.01 - EP US); C12N 2502/1323 (2013.01 - EP US)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

DE 102015119880 A1 20170518; DE 102015119880 B4 20180524; AU 2016357986 A1 20180621; CN 108473951 A 20180831; EP 3377616 A1 20180926; JP 2018533960 A 20181122; JP 2022031757 A 20220222; JP 7370613 B2 20231030; US 11174463 B2 20211116; US 2020255799 A1 20200813; WO 2017084999 A1 20170526

DOCDB simple family (application)

DE 102015119880 A 20151117; AU 2016357986 A 20161114; CN 201680078151 A 20161114; EP 16797504 A 20161114; EP 2016077541 W 20161114; JP 2018525687 A 20161114; JP 2021188693 A 20211119; US 201615776359 A 20161114