EP 3389840 B1 20190821 - MICROPARTICLE PRODUCTION PROCESS AND APPARATUS
Title (en)
MICROPARTICLE PRODUCTION PROCESS AND APPARATUS
Title (de)
VERFAHREN UND VORRICHTUNGEN ZUR HERSTELLUNG VON MIKROPARTIKELN
Title (fr)
PROCÉDÉ ET APPAREIL DE PRODUCTION DE MICROPARTICULES
Publication
Application
Priority
- GB 201522423 A 20151218
- EP 2016081436 W 20161216
Abstract (en)
[origin: WO2017103113A2] Provided is an apparatus for producing solid polymeric microparticles, the apparatus comprising a plurality of liquid droplet generators for forming liquid droplets of a first liquid, and a nozzle for forming a jet of a second liquid, wherein the plurality of liquid droplet generators and the nozzle are arranged relative to each other such that, in use, liquid droplets from the plurality of liquid droplet generators pass through a gas into said jet of second liquid. Also provided is a process for producing solid microparticles, the process comprising: providing a first liquid comprising a solute and a solvent, the solute comprising a biocompatible polymer, the concentration of polymer in the first liquid being at least 10% w/v, 'w' being the weight of the polymer and 'ν' being the volume of the solvent, providing a plurality of liquid droplet generators operable to generate liquid droplets, providing a jet of a second liquid, causing the plurality of liquid droplet generators to form liquid droplets of the first liquid, passing the liquid droplets through a gas to contact the jet of the second liquid so as to cause the solvent to exit the droplets, thus forming solid microparticles, the solubility of the solvent in the second liquid being at least 5g of solvent per 100ml of second liquid, the solvent being substantially miscible with the second liquid.
IPC 8 full level
B01J 2/04 (2006.01); B01J 2/08 (2006.01); B01J 2/18 (2006.01)
CPC (source: EP GB KR US)
A61K 9/16 (2013.01 - KR); A61K 9/51 (2013.01 - KR); A61P 25/00 (2018.01 - EP); A61P 27/02 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 31/04 (2018.01 - EP); A61P 35/00 (2018.01 - EP); B01J 2/04 (2013.01 - EP KR US); B01J 2/06 (2013.01 - GB US); B01J 2/08 (2013.01 - EP GB KR US); B01J 2/18 (2013.01 - EP KR US); B29B 9/10 (2013.01 - EP); B29B 2009/125 (2013.01 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2017103113 A2 20170622; WO 2017103113 A3 20170824; AU 2016369412 A1 20180614; AU 2016369412 B2 20210401; BR 112018012340 A2 20181204; BR 112018012340 B1 20210309; CA 3008554 A1 20170622; CN 108602035 A 20180928; CN 108602035 B 20211015; EP 3389840 A2 20181024; EP 3389840 B1 20190821; ES 2749949 T3 20200324; GB 201522423 D0 20160203; GB 2551944 A 20180110; GB 2551944 B 20210901; JP 2019507003 A 20190314; JP 7112325 B2 20220803; KR 102681302 B1 20240703; KR 20180111800 A 20181011; MX 2018007466 A 20181114; PL 3389840 T3 20200131; US 10981131 B2 20210420; US 11794158 B2 20231024; US 2019193037 A1 20190627; US 2021268461 A1 20210902
DOCDB simple family (application)
EP 2016081436 W 20161216; AU 2016369412 A 20161216; BR 112018012340 A 20161216; CA 3008554 A 20161216; CN 201680074439 A 20161216; EP 16812959 A 20161216; ES 16812959 T 20161216; GB 201522423 A 20151218; JP 2018531164 A 20161216; KR 20187020613 A 20161216; MX 2018007466 A 20161216; PL 16812959 T 20161216; US 201615780211 A 20161216; US 202117204676 A 20210317