EP 3395809 A1 20181031 - BENZOPIPERIDINE DERIVATIVE, PREPARATION METHOD THEREOF AND MEDICAL USE THEREOF
Title (en)
BENZOPIPERIDINE DERIVATIVE, PREPARATION METHOD THEREOF AND MEDICAL USE THEREOF
Title (de)
BENZOPIPERIDINDERIVAT, HERSTELLUNGSVERFAHREN DAFÜR UND MEDIZINISCHE VERWENDUNG DAVON
Title (fr)
DÉRIVÉ DE BENZOPIPÉRIDINE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION MÉDICALE
Publication
Application
Priority
- CN 201510975923 A 20151222
- CN 2016108367 W 20161202
Abstract (en)
The present invention relates to a benzopiperidine derivative, a preparation method thereof and a medical use thereof. In particular, the present invention relates to a benzopiperidine derivative as shown by general formula (I), a preparation method thereof and a pharmaceutical composition containing the derivative, as well as a use thereof as an estrogen receptor modulator in the prevention and/or treatment of estrogen receptor-mediated or dependent diseases or conditions. Preferably, the disease is breast cancer. The substituents in the general formula (I) are the same as those defined in the description.
IPC 8 full level
C07D 401/04 (2006.01); A61K 31/4725 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP KR RU US)
A61K 31/435 (2013.01 - RU); A61K 31/4725 (2013.01 - EP KR RU US); A61P 1/00 (2017.12 - RU); A61P 1/16 (2017.12 - RU); A61P 3/00 (2017.12 - RU); A61P 3/04 (2017.12 - RU); A61P 7/00 (2017.12 - RU); A61P 7/02 (2017.12 - RU); A61P 9/00 (2017.12 - KR RU); A61P 9/10 (2017.12 - RU); A61P 9/12 (2017.12 - RU); A61P 13/02 (2017.12 - RU); A61P 15/00 (2017.12 - RU); A61P 15/08 (2017.12 - RU); A61P 19/00 (2017.12 - RU); A61P 19/02 (2017.12 - RU); A61P 19/10 (2017.12 - RU); A61P 21/00 (2017.12 - RU); A61P 25/00 (2017.12 - KR RU); A61P 25/02 (2017.12 - RU); A61P 25/06 (2017.12 - RU); A61P 25/14 (2017.12 - RU); A61P 25/16 (2017.12 - RU); A61P 25/18 (2017.12 - RU); A61P 25/24 (2017.12 - RU); A61P 25/28 (2017.12 - RU); A61P 25/32 (2017.12 - RU); A61P 29/00 (2017.12 - RU); A61P 31/00 (2017.12 - RU); A61P 35/00 (2017.12 - EP KR RU US); A61P 35/02 (2017.12 - RU); A61P 37/02 (2017.12 - RU); A61P 43/00 (2017.12 - RU); C07D 401/04 (2013.01 - EP KR RU US); C07D 417/04 (2013.01 - EP RU US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 3395809 A1 20181031; EP 3395809 A4 20190619; AU 2016379672 A1 20180621; BR 112018011817 A2 20181204; CA 3006683 A1 20170629; CN 107428721 A 20171201; CN 107428721 B 20200728; HK 1244808 A1 20180817; JP 2019503346 A 20190207; KR 20180095564 A 20180827; MX 2018007844 A 20190121; RU 2727705 C1 20200723; TW 201722929 A 20170701; TW I732810 B 20210711; US 10398689 B2 20190903; US 2018318284 A1 20181108; WO 2017107754 A1 20170629
DOCDB simple family (application)
EP 16877565 A 20161202; AU 2016379672 A 20161202; BR 112018011817 A 20161202; CA 3006683 A 20161202; CN 2016108367 W 20161202; CN 201680013279 A 20161202; HK 18104375 A 20180402; JP 2018528988 A 20161202; KR 20187019436 A 20161202; MX 2018007844 A 20161202; RU 2018121642 A 20161202; TW 105142052 A 20161219; US 201616061676 A 20161202