EP 3416950 A1 20181226 - MAX BINDERS AS MYC MODULATORS AND USES THEREOF
Title (en)
MAX BINDERS AS MYC MODULATORS AND USES THEREOF
Title (de)
MAX-BINDER ALS MYC-MODULATOREN UND VERWENDUNGEN DAVON
Title (fr)
LIANTS DE MAX COMME MODULATEURS DE MYC ET LEURS UTILISATIONS
Publication
Application
Priority
- US 201662295996 P 20160216
- US 2017018162 W 20170216
Abstract (en)
[origin: CA3012846A1] The present disclosure provides compounds of Formula (I'), Formula (I), Formula (II), Formula (II-A), Formula (III), and Formula (IV). The compounds described herein are MAX binders and/or modulators of Myc, Mad, or Mxil (e.g., inhibitors of Myc, Mad, or Mxil), and may be useful in treating a subject with a disease associated with Myc, such as proliferative diseases ( e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions and kits including the compounds described herein, as well as methods of using and uses of the compounds, compositions, and kits.
IPC 8 full level
C07D 233/28 (2006.01); A61K 31/55 (2006.01); A61P 35/00 (2006.01); C07D 491/107 (2006.01); C07D 498/04 (2006.01); C07D 498/10 (2006.01)
CPC (source: EP KR US)
A61K 31/55 (2013.01 - KR); A61P 7/00 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP KR); A61P 43/00 (2017.12 - EP); C07D 233/28 (2013.01 - EP KR US); C07D 491/107 (2013.01 - EP KR US); C07D 498/04 (2013.01 - EP KR US); C07D 498/10 (2013.01 - EP KR US)
Citation (search report)
See references of WO 2017143059A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
US 10106555 B2 20181023; US 2017233405 A1 20170817; AU 2017221422 A1 20180816; BR 112018016133 A2 20190102; CA 3012846 A1 20170824; CN 109071456 A 20181221; EP 3416950 A1 20181226; JP 2019505548 A 20190228; KR 20180107261 A 20181001; MX 2018009913 A 20181129; RU 2018132559 A 20200317; US 10865213 B2 20201215; US 2019144466 A1 20190516; WO 2017143059 A1 20170824
DOCDB simple family (application)
US 201715435003 A 20170216; AU 2017221422 A 20170216; BR 112018016133 A 20170216; CA 3012846 A 20170216; CN 201780011783 A 20170216; EP 17708095 A 20170216; JP 2018543356 A 20170216; KR 20187026354 A 20170216; MX 2018009913 A 20170216; RU 2018132559 A 20170216; US 2017018162 W 20170216; US 201816167238 A 20181022