EP 3423094 A4 20191106 - GFRAL RECEPTOR THERAPIES
Title (en)
GFRAL RECEPTOR THERAPIES
Title (de)
GFRAL-REZEPTORTHERAPIEN
Title (fr)
TRAITEMENTS IMPLIQUANT LE RÉCEPTEUR GFRAL
Publication
Application
Priority
CN 2016074809 W 20160229
Abstract (en)
[origin: WO2017147742A1] The present invention relates to the field of medicine. More particularly, the invention relates to a method of treating diabetes or obesity by agonizing the GFRAL receptor, a compound for use in such treatment and pharmaceutical compositions containing such a compound. The invention also relates to a method of treating cachexia by antagonizing, inhibiting, neutralizing or blocking the GFRAL receptor, a compound for use in such treatment and pharmaceutical compositions containing such a compound.
IPC 8 full level
A61K 39/395 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); A61P 3/04 (2006.01); A61P 3/08 (2006.01); A61P 3/10 (2006.01)
CPC (source: EP)
A61K 38/179 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); A61P 1/14 (2017.12); A61P 3/04 (2017.12); A61P 3/08 (2017.12); A61P 3/10 (2017.12); A61P 43/00 (2017.12); C07K 16/22 (2013.01); A61K 2039/505 (2013.01)
Citation (search report)
- [E] WO 2017121865 A1 20170720 - NOVO NORDISK AS [DK]
- [XY] WO 03076569 A2 20030918 - GENENTECH INC [US]
- [XI] EP 2694092 A2 20140212 - AMGEN INC [US]
- [Y] VICKY W. W. TSAI ET AL: "Anorexia/cachexia of chronic diseases: a role for the TGF-β family cytokine MIC-1/GDF15", JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE, vol. 3, no. 4, 31 December 2012 (2012-12-31), pages 239 - 243, XP055105895, ISSN: 2190-5991, DOI: 10.1007/s13539-012-0082-6
- See references of WO 2017147742A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2017147742 A1 20170908; CN 108697795 A 20181023; EP 3423094 A1 20190109; EP 3423094 A4 20191106; JP 2019510739 A 20190418
DOCDB simple family (application)
CN 2016074809 W 20160229; CN 201680082844 A 20160229; EP 16891935 A 20160229; JP 2018540415 A 20160229