EP 3423469 A1 20190109 - NEW TRIFLUOROMETHYLPROPANAMIDE DERIVATIVES AS HTRA1 INHIBITORS
Title (en)
NEW TRIFLUOROMETHYLPROPANAMIDE DERIVATIVES AS HTRA1 INHIBITORS
Title (de)
NEUE TRIFLUORMETHYLPROPANAMIDDERIVATE ALS HTRA1-INHIBITOREN
Title (fr)
NOUVEAUX DÉRIVÉS DE TRIFLUOROMÉTHYLPROPANAMIDE UTILISÉS COMME INHIBITEURS DE HTRA1
Publication
Application
Priority
- EP 16158637 A 20160304
- EP 2017054677 W 20170301
Abstract (en)
[origin: WO2017148964A1] The invention provides serine protease HTRA1 inhibiting compounds having the general formula (I) wherein R 2, R 3, R 4, R 5, R 6, R 7, R 3, R 8, R 10, R 11and R 23 are as described herein. These compounds are suitable for the treatment of ocular diseases such as age-related macular degeneration and others.
IPC 8 full level
A61K 31/4402 (2006.01); A61P 27/00 (2006.01); C07K 5/062 (2006.01); C07K 5/065 (2006.01); C07K 5/068 (2006.01); C07K 5/072 (2006.01); C07K 5/078 (2006.01); C07K 5/083 (2006.01)
CPC (source: EP US)
A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 27/00 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 5/06026 (2013.01 - EP US); C07K 5/06078 (2013.01 - EP US); C07K 5/06086 (2013.01 - EP US); C07K 5/06121 (2013.01 - EP US); C07K 5/06139 (2013.01 - EP US); C07K 5/06191 (2013.01 - EP US); C07K 5/0804 (2013.01 - US); C07K 5/0806 (2013.01 - EP US); C07K 5/081 (2013.01 - EP US); C07K 5/0812 (2013.01 - EP US); C07K 5/0815 (2013.01 - EP US); C07K 5/0819 (2013.01 - EP US); C07K 5/0821 (2013.01 - EP US); C07K 5/0827 (2013.01 - EP US)
Citation (search report)
See references of WO 2017148964A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2017148964 A1 20170908; CN 108699106 A 20181023; CN 108699106 B 20211130; EP 3423469 A1 20190109; HK 1257565 A1 20191025; JP 2019513698 A 20190530; US 11014963 B2 20210525; US 2018371016 A1 20181227
DOCDB simple family (application)
EP 2017054677 W 20170301; CN 201780013095 A 20170301; EP 17707059 A 20170301; HK 18116650 A 20181227; JP 2018546490 A 20170301; US 201816121300 A 20180904