Global Patent Index - EP 3431472 A4

EP 3431472 A4 20191218 - NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME

Title (en)

NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME

Title (de)

NEUARTIGE VERBINDUNG ZUR HEMMUNG DER NICOTINAMID-PHOSPHORIBOSYL-TRANSFERASE UND ZUSAMMENSETZUNG DAMIT

Title (fr)

NOUVEAU COMPOSÉ POUR INHIBER LA NICOTINAMIDE PHOSPHORIBOSYLTRANSFÉRASE ET COMPOSITION CONTENANT LE NOUVEAU COMPOSÉ

Publication

EP 3431472 A4 20191218 (EN)

Application

EP 17767017 A 20170317

Priority

  • US 201662309557 P 20160317
  • KR 2017002895 W 20170317

Abstract (en)

[origin: EP3431472A2] The present invention relates to a novel compounds for inhibiting nicotinamide phosphoribosyltransferase (NamPT), a composition comprising the same, and various uses thereof.

IPC 8 full level

C07D 403/06 (2006.01); A61K 31/47 (2006.01); A61K 31/496 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01)

CPC (source: EP KR US)

A23L 33/10 (2016.07 - KR); A61K 8/4926 (2013.01 - KR); A61K 31/437 (2013.01 - KR); A61K 31/47 (2013.01 - EP); A61K 31/496 (2013.01 - EP); A61P 35/00 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61Q 19/00 (2013.01 - KR); C07D 209/14 (2013.01 - US); C07D 213/82 (2013.01 - US); C07D 277/82 (2013.01 - US); C07D 401/12 (2013.01 - US); C07D 403/06 (2013.01 - EP); C07D 403/12 (2013.01 - EP); C07D 405/12 (2013.01 - US); C07D 413/12 (2013.01 - EP KR US); C07D 417/12 (2013.01 - US); C07D 417/14 (2013.01 - US); C07D 419/14 (2013.01 - US); C07D 471/04 (2013.01 - KR US); C07D 498/04 (2013.01 - US); C07D 513/04 (2013.01 - US); A23V 2002/00 (2013.01 - KR); A23V 2200/30 (2013.01 - KR)

Citation (search report)

  • [X] WO 9962885 A1 19991209 - BOEHRINGER INGELHEIM PHARMA [US]
  • [XI] HONG C. SHEN ET AL: "Discovery of Inhibitors of Soluble Epoxide Hydrolase: A Target with Multiple Potential Therapeutic Indications", JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, no. 5, 8 March 2012 (2012-03-08), pages 1789 - 1808, XP055190495, ISSN: 0022-2623, DOI: 10.1021/jm201468j
  • [X] LLUÍS BALLELL ET AL: "Supporting Information - Fueling Open-Source Drug Discovery: 177 Small-Molecule Leads against Tuberculosis", CHEMMEDCHEM, 1 February 2013 (2013-02-01), Weinheim, pages 1 - 116, XP055514842, Retrieved from the Internet <URL:https://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002/cmdc.201200428&file=cmdc_201200428_sm_miscellaneous_information.pdf> [retrieved on 20181012], DOI: 10.1002/cmdc.201200428
  • [X] BUKHTIAROVA T A ET AL: "Structure and antiinflammatory activity of Isonicotinic and Nicotinic Amides", PHARMACEUTICAL CHEMISTRY JOURNAL, SPRINGER NEW YORK LLC, US, vol. 31, no. 11, 1 January 1997 (1997-01-01), pages 597 - 599, XP002501345, ISSN: 0091-150X, DOI: 10.1007/BF02464277
  • [X] HO YIN LO ET AL: "Substituted pyrazoles as novel sEH antagonist: Investigation of key binding interactions within the catalytic domain", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 22, 1 November 2010 (2010-11-01), AMSTERDAM, NL, pages 6379 - 6383, XP055608894, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2010.09.095
  • [X] VLADIMÍR VALENTA ET AL: "Synthesis of several 4-hydroxy-3,5-dimethoxybenzamides, their O-substituted derivatives and some related compounds as potential neurotropic agents", COLLECTION SYMPOSIUM SERIES (XIIITH SYMPOSIUM ON CHEMISTRY OF NUCLEIC ACID COMPONENTS SPINDLERUV MLYN, CZECH REPUBLIC; SEPTEMBER 03 -09, 2005), vol. 50, no. 2, 1 January 1985 (1985-01-01), CZ, pages 510 - 518, XP055608926, ISSN: 0010-0765, ISBN: 978-80-86241-25-8, DOI: 10.1135/cccc19850510
  • [X] SAM J ET AL: "HYPOTENSIVE AGENTS. PYRIDINECARBOXAMIDES AND PIPERIDINECARBOXAMIDES", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 81, no. 3, 1 January 1959 (1959-01-01), pages 710 - 713, XP008062772, ISSN: 0002-7863, DOI: 10.1021/JA01512A051
  • See references of WO 2017160116A2

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

EP 3431472 A2 20190123; EP 3431472 A4 20191218; EP 3431472 B1 20230503; CN 108779104 A 20181109; CN 108779104 B 20210413; JP 2019512503 A 20190516; JP 7010834 B2 20220210; KR 101893997 B1 20180831; KR 101894001 B1 20180831; KR 101894004 B1 20180831; KR 102382188 B1 20220405; KR 20170108885 A 20170927; KR 20170108886 A 20170927; KR 20170108887 A 20170927; KR 20180036666 A 20180409; US 11078195 B2 20210803; US 11795163 B2 20231024; US 2020247795 A1 20200806; US 2021171513 A1 20210610; WO 2017160116 A2 20170921; WO 2017160116 A3 20171012; WO 2017160116 A9 20171130

DOCDB simple family (application)

EP 17767017 A 20170317; CN 201780018060 A 20170317; JP 2018548663 A 20170317; KR 2017002895 W 20170317; KR 20170033880 A 20170317; KR 20170033881 A 20170317; KR 20170033882 A 20170317; KR 20180034662 A 20180326; US 201716085774 A 20170317; US 202017119950 A 20201211