EP 3432914 A4 20191113 - BIOAVAILABLE POLYAMINES
Title (en)
BIOAVAILABLE POLYAMINES
Title (de)
BIOVERFÜGBARE POLYAMINE
Title (fr)
POLYAMIDES BIODISPONIBLES
Publication
Application
Priority
- US 201662313657 P 20160325
- US 2017023250 W 20170320
Abstract (en)
[origin: WO2017165313A1] Disclosed herein are pharmaceutical salts of a cationic protonated polyamine pharmaceutical agent and an anionic organic carboxylate which is hydrophobic when in protonated form, particularly suited for oral administration, where these salts have good bioavailability in solid dosage forms and may be used in the treatment of cancer and other medical conditions for which the pharmaceutical agent is intended.
IPC 8 full level
A61K 9/20 (2006.01); A23L 33/00 (2016.01); A61K 9/28 (2006.01); A61K 31/78 (2006.01); A61K 38/45 (2006.01); A61K 45/06 (2006.01)
CPC (source: EP KR US)
A61K 9/0053 (2013.01 - KR); A61K 9/2054 (2013.01 - EP US); A61K 9/2846 (2013.01 - EP US); A61K 9/2886 (2013.01 - EP US); A61K 31/785 (2013.01 - EP KR US); A61K 45/06 (2013.01 - EP US); A61P 35/00 (2018.01 - EP KR US); C07C 53/126 (2013.01 - EP); C07C 237/06 (2013.01 - EP); C07C 237/22 (2013.01 - EP); C07B 2200/07 (2013.01 - EP); C07C 2601/14 (2017.05 - EP)
C-Set (source: EP)
Citation (search report)
- [I] US 6963010 B2 20051108 - BURNS MARK R [US], et al
- [A] MAHER S ET AL: "Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER, AMSTERDAM, NL, vol. 61, no. 15, 17 December 2009 (2009-12-17), pages 1427 - 1449, XP026761597, ISSN: 0169-409X, [retrieved on 20091001], DOI: 10.1016/J.ADDR.2009.09.006
- See also references of WO 2017165313A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2017165313 A1 20170928; AU 2017236905 A1 20180906; AU 2017236905 B2 20240328; CA 3015849 A1 20170928; CN 109069594 A 20181221; CN 109069594 B 20220308; CY 1123636 T1 20220324; DK 3432914 T3 20201130; DK 3785706 T3 20230911; EA 037149 B1 20210211; EA 201892175 A1 20190228; EP 3432914 A1 20190130; EP 3432914 A4 20191113; EP 3432914 B1 20200923; EP 3785706 A1 20210303; EP 3785706 B1 20230607; ES 2836289 T3 20210624; ES 2955255 T3 20231129; HR P20201844 T1 20210402; HU E052620 T2 20210528; IL 261512 A 20181031; JP 2019513153 A 20190523; JP 6949098 B2 20211013; KR 102454783 B1 20221013; KR 20180123133 A 20181114; LT 3432914 T 20201210; MX 2018010768 A 20181129; PL 3432914 T3 20210308; PT 3432914 T 20201224; SI 3432914 T1 20210129; US 10632145 B2 20200428; US 11395834 B2 20220726; US 2019008892 A1 20190110; US 2020352983 A1 20201112; US 2023088829 A1 20230323
DOCDB simple family (application)
US 2017023250 W 20170320; AU 2017236905 A 20170320; CA 3015849 A 20170320; CN 201780023734 A 20170320; CY 201101192 T 20201216; DK 17770923 T 20170320; DK 20196042 T 20170320; EA 201892175 A 20170320; EP 17770923 A 20170320; EP 20196042 A 20170320; ES 17770923 T 20170320; ES 20196042 T 20170320; HR P20201844 T 20201120; HU E17770923 A 20170320; IL 26151218 A 20180902; JP 2019500737 A 20170320; KR 20187030395 A 20170320; LT 17770923 T 20170320; MX 2018010768 A 20170320; PL 17770923 T 20170320; PT 17770923 T 20170320; SI 201730526 T 20170320; US 201715753291 A 20170320; US 202016823150 A 20200318; US 202217808174 A 20220622