EP 3434292 B1 20230823 - COMPOSITE BLOOD VESSEL SUBSTITUTE AND THE METHOD FOR PRODUCING IT
Title (en)
COMPOSITE BLOOD VESSEL SUBSTITUTE AND THE METHOD FOR PRODUCING IT
Title (de)
ZUSAMMENGESETZTER BLUTGEFÄSSERSATZ UND VERFAHREN ZUR HERSTELLUNG DAVON
Title (fr)
SUBSTITUT DE VAISSEAU SANGUIN COMPOSITE ET SON PROCÉDÉ DE PRODUCTION
Publication
Application
Priority
CZ 2017427 A 20170726
Abstract (en)
[origin: EP3434292A1] The present invention relates to a composite vascular substitute, in particular for flow rates under 100 ml/min and inner diameters under 6 mm, which contains a non-resorbable knitted fabric layer (2), which is provided on the inner and outer sides with a collagen compound coating of freshwater fish - Czech carp. The non-resorbable knitted fabric compound (2) is preferably placed on a self-supporting resorbable collagen compound layer (1), wherein the non-resorbable layer (2) is covered with an intermediate collagen compound layer (4) overlaid with an outer, resorbable collagen compound layer (3). Furthermore, it relates to the method for producing this vascular substitute, wherein the collagen compound with a collagen concentration of 4 to 12% by weight is kept at 15 to 30 °C for 18 to 30 hours, and then the non-resorbable knitted fabric layer 2 is integrated in one collagen compound layer to make a collagen compound coating on the inner and outer sides of the non-resorbable knitted fabric layer 2, or the collagen compound with a collagen concentration of 4 to 12% by weight is kept at 15 to 30 °C for 18 to 30 hours, and then the collagen compound is extruded to make the inner resorbable layer (1) in the form of a tube that is dried at the room temperature until pliable, and the inner resorbable layer (1) is overlaid with the non-resorbable knitted fabric layer (2), on which the outer resorbable layer (3) of collagen compound with a collagen concentration of 3 to 12% by weight is extruded, and the vascular substitutes are dried at 15 to 30 °C for 15 to 30 hours until pliable, and then the vascular substitutes are hardened with 1.5 to 3.2% resin for 3 to 10 minutes and then they are dried and softened up in a 15 to 30% glycerine bath for 15 to 25 minutes.
IPC 8 full level
A61L 27/24 (2006.01); A61L 27/48 (2006.01); A61L 27/50 (2006.01); A61L 27/58 (2006.01)
CPC (source: CZ EP)
A61F 2/06 (2013.01 - CZ); A61L 27/18 (2013.01 - CZ); A61L 27/24 (2013.01 - CZ EP); A61L 27/40 (2013.01 - CZ); A61L 27/48 (2013.01 - EP); A61L 27/507 (2013.01 - EP); A61L 27/58 (2013.01 - CZ EP); B29C 48/13 (2019.01 - CZ); B29C 48/151 (2019.01 - CZ); B32B 37/153 (2013.01 - CZ); A61F 2250/0051 (2013.01 - CZ)
C-Set (source: EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3434292 A1 20190130; EP 3434292 B1 20230823; CZ 2017427 A3 20190206; CZ 308556 B6 20201125
DOCDB simple family (application)
EP 18185629 A 20180725; CZ 2017427 A 20170726