EP 3443990 A4 20190508 - COMPOSITE EXTRACELLULAR MATRIX BIOMATERIAL

Title (en)

COMPOSITE EXTRACELLULAR MATRIX BIOMATERIAL

Title (de)

ZUSAMMENGESETZTES BIOMATERIAL FÜR EXTRAZELLULÄRE MATRIX

Title (fr)

BIOMATÉRIAU COMPOSITE DE TYPE MATRICE EXTRACELLULAIRE

Publication

EP 3443990 A4 20190508 (EN)

Application

EP 17788509 A 20170213

Priority

CN 201610261472 A 20160425
CN 2017073394 W 20170213

Abstract (en)

[origin: EP3443990A1] A composite extracellular matrix biomaterial, with a middle layer comprising a decellularized small intestinal submucosa (SIS) (1), and a top layer and a bottom layer comprising a decellularized urinary bladder matrix (UBM) (2). The top and bottom layers completely cover the middle layer, thereby forming a sandwich structure. The sandwich structure allows the UBM (2) to isolate an antigenic property of the SIS (1) and to allowing the UBM to directly contact a host tissue, thereby realizing a high tissue compatibility. The SIS (1) can compensate for a shortcoming of low mechanical strength of the UBM (2). The composite extracellular matrix biomaterial can be used to fill, strengthen, repair, or reconstruct a damage or defect of a fascia, meninges, pleura, pelvic floor, dermis, solid organ, and various types of soft tissues.

IPC 8 full level

A61L 27/36 (2006.01); A61L 27/40 (2006.01); A61L 27/50 (2006.01)

CPC (source: CN EP US)

A61L 27/3604 (2013.01 - CN EP US); A61L 27/3629 (2013.01 - CN EP US); A61L 27/3633 (2013.01 - EP US); A61L 27/3683 (2013.01 - EP); A61L 27/3691 (2013.01 - US); A61L 27/3891 (2013.01 - US); A61L 27/50 (2013.01 - CN); A61L 2430/34 (2013.01 - CN); A61L 2430/40 (2013.01 - EP US)

Citation (search report)

[I] US 2011020420 A1 20110127 - BOSLEY JR RODNEY W [US], et al
[A] EP 1177800 A1 20020206 - DEPUY ORTHOPAEDICS INC [US]
[A] WO 2009070686 A1 20090604 - COOK BIOTECH INC [US], et al
See references of WO 2017185853A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

EP 3443990 A1 20190220; EP 3443990 A4 20190508; EP 3443990 B1 20200930; CN 105920669 A 20160907; CN 105920669 B 20190329; JP 2019513514 A 20190530; JP 6827522 B2 20210210; US 2019314553 A1 20191017; WO 2017185853 A1 20171102

DOCDB simple family (application)

EP 17788509 A 20170213; CN 201610261472 A 20160425; CN 2017073394 W 20170213; JP 2019503607 A 20170213; US 201716095633 A 20170213