Global Patent Index - EP 3450978 A4

EP 3450978 A4 20191120 - INDEX OF LOCAL SEVERITY OF ATOPIC DERMATITIS IN SKIN AND THERAPEUTIC EFFECT THEREON

Title (en)

INDEX OF LOCAL SEVERITY OF ATOPIC DERMATITIS IN SKIN AND THERAPEUTIC EFFECT THEREON

Title (de)

INDEX DER LOKALEN AUSPRÄGUNG VON ATOPISCHER DERMATITIS IN DER HAUT UND THERAPEUTISCHE WIRKUNG DARAUF

Title (fr)

INDICE DE GRAVITÉ LOCALE DE DERMATITE ATOPIQUE DANS LA PEAU ET DE L'EFFET THÉRAPEUTIQUE SUR CETTE DERNIÈRE

Publication

EP 3450978 A4 20191120 (EN)

Application

EP 17789384 A 20170419

Priority

  • JP 2016092020 A 20160428
  • JP 2017015792 W 20170419

Abstract (en)

[origin: EP3450978A1] Provided is an objective and convenient index for judging full recovery from atopic dermatitis and severity thereof. The present invention provides a diagnosis assisting method for determining a treatment policy for an atopic dermatitis subject under the treatment, said method comprising: measuring the expression value of SCCA-1 in skin horny cells of the subject; i) when the SCCA-1 expression value is not statistically significantly higher than the level of those who do not suffer from atopic dermatitis, then determining that the continuation of the treatment for the disease becomes unnecessary thanks to the treatment; and, in the case where the continuation of the treatment is determined as still necessary, ii) ranking the severity of atopic dermatitis of the subject using the SCCA-1 expression value as an index and determining an adequate treatment method for atopic dermatitis to be given to the subject depending on the rank.

IPC 8 full level

G01N 33/53 (2006.01); C12Q 1/04 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP KR US)

G01N 33/53 (2013.01 - KR); G01N 33/543 (2013.01 - US); G01N 33/6881 (2013.01 - EP KR US); G06F 17/18 (2013.01 - US); G16H 50/30 (2017.12 - US); G01N 2333/8121 (2013.01 - EP US); G01N 2800/202 (2013.01 - EP US); G01N 2800/52 (2013.01 - EP KR US); G01N 2800/56 (2013.01 - KR)

Citation (search report)

  • [I] EP 1860437 A1 20071128 - SHISEIDO CO LTD [JP]
  • [I] CAROLYN J BROCCARDO ET AL: "Peeling off the layers: Skin taping and a novel proteomics approach to study atopic dermatitis", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 124, no. 5, 1 November 2009 (2009-11-01), pages 1113 - 1115.e11, XP055062125, ISSN: 0091-6749, DOI: 10.1016/j.jaci.2009.07.057
  • [A] MITSUISHI K ET AL: "The squamous cell carcinoma antigens as relevant biomarkers of atopic dermatitis", CLINICAL & EXPERIMENTAL ALLERGY : JOURNAL OF THE BRITISH SOCIETY FOR ALLERGY AND CLINICAL IMMUNOLOGY, WILEY INTERSCIENCE, UK, vol. 35, no. 10, 1 January 2005 (2005-01-01), pages 1327 - 1333, XP003017844, ISSN: 0954-7894, DOI: 10.1111/J.1365-2222.2005.02353.X
  • [A] DAVID A EWALD ET AL: "Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways", BMC MEDICAL GENOMICS, BIOMED CENTRAL LTD, LONDON UK, vol. 8, no. 1, 12 October 2015 (2015-10-12), pages 60, XP021229756, ISSN: 1755-8794, DOI: 10.1186/S12920-015-0133-X
  • See references of WO 2017188101A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

EP 3450978 A1 20190306; EP 3450978 A4 20191120; CN 109073640 A 20181221; JP 2017198632 A 20171102; JP 6835479 B2 20210224; KR 20190004269 A 20190111; TW 201738561 A 20171101; US 2019145967 A1 20190516; WO 2017188101 A1 20171102

DOCDB simple family (application)

EP 17789384 A 20170419; CN 201780026073 A 20170419; JP 2016092020 A 20160428; JP 2017015792 W 20170419; KR 20187030966 A 20170419; TW 106113103 A 20170419; US 201716096861 A 20170419