Global Patent Index - EP 3464339 A4

EP 3464339 A4 20191225 - B-TYPE NATRIURETIC PEPTIDE PROTEOLYTIC ASSAY FOR CARDIOVASCULAR DISEASE RISK ASSESSMENT

Title (en)

B-TYPE NATRIURETIC PEPTIDE PROTEOLYTIC ASSAY FOR CARDIOVASCULAR DISEASE RISK ASSESSMENT

Title (de)

PROTEOLYTISCHER TEST VON B-TYP-NATRIURETISCHEM PEPTID ZUR BEURTEILUNG DES RISIKOS VON HERZ-KREISLAUF-ERKRANKUNGEN

Title (fr)

DOSAGE PROTÉOLYTIQUE DU PEPTIDE NATRIURÉTIQUE DE TYPE B POUR L'ÉVALUATION DU RISQUE DE MALADIE CARDIOVASCULAIRE

Publication

EP 3464339 A4 20191225 (EN)

Application

EP 17807518 A 20170601

Priority

  • US 201662345595 P 20160603
  • US 2017035544 W 20170601

Abstract (en)

[origin: WO2017210488A1] Described herein are methods for assessing the risk of cardiovascular disease in a subject in need thereof by detecting the presence of one or more cleavage products of the one or more natriuretic peptides over a period of time, wherein the presence of one or more cleavage products is indicative of an increased risk of the subject developing cardiovascular disease.

IPC 8 full level

C07K 14/58 (2006.01); G01N 33/573 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01)

CPC (source: EP)

C07K 14/58 (2013.01); C12Q 1/37 (2013.01); G01N 33/6893 (2013.01); G01N 33/74 (2013.01); G01N 2333/58 (2013.01); G01N 2800/325 (2013.01); G01N 2800/326 (2013.01); G01N 2800/50 (2013.01)

Citation (search report)

  • [XY] WO 2008030901 A2 20080313 - ABBOTT LAB [US], et al
  • [Y] J. Y. Y. FOO ET AL: "Circulating Fragments of N-Terminal Pro-B-Type Natriuretic Peptides in Plasma of Heart Failure Patients", CLINICAL CHEMISTRY, vol. 59, no. 10, 1 October 2013 (2013-10-01), pages 1523 - 1531, XP055368001, ISSN: 0009-9147, DOI: 10.1373/clinchem.2012.200204
  • [A] ZHANG SAN-MING ET AL: "Association between serum corin levels and risk of acute myocardial infarction", CLINICA CHIMICA ACTA, ELSEVIER BV, AMSTERDAM, NL, vol. 452, 11 November 2015 (2015-11-11), pages 134 - 137, XP029365998, ISSN: 0009-8981, DOI: 10.1016/J.CCA.2015.11.012
  • [T] SHENYAN ZHANG ET AL: "Profiling B-Type Natriuretic Peptide Cleavage Peptidoforms in Human Plasma by Capillary Electrophoresis with Electrospray Ionization Mass Spectrometry", JOURNAL OF PROTEOME RESEARCH, vol. 16, no. 12, 1 September 2017 (2017-09-01), pages 4515 - 4522, XP055641736, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.7b00482
  • See references of WO 2017210488A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2017210488 A1 20171207; EP 3464339 A1 20190410; EP 3464339 A4 20191225

DOCDB simple family (application)

US 2017035544 W 20170601; EP 17807518 A 20170601