EP 3466421 B1 20221130 - COMPOSITION FOR THE TREATMENT OF PERIPHERAL NERVE DISORDERS
Title (en)
COMPOSITION FOR THE TREATMENT OF PERIPHERAL NERVE DISORDERS
Title (de)
ZUSAMMENSETZUNG ZUR BEHANDLUNG VON PERIPHEREN NERVENERKRANKUNGEN
Title (fr)
COMPOSITION DESTINÉE AU TRAITEMENT DES TROUBLES DU SYSTÈME NERVEUX PÉRIPHÉRIQUE
Publication
Application
Priority
- JP 2016102878 A 20160523
- JP 2017019067 W 20170522
Abstract (en)
[origin: EP3466421A1] The present invention provides a means for treating and/or preventing peripheral nerve disorder by facilitating regeneration of peripheral nerves. Specifically, the present invention provides a composition for treating and/or preventing peripheral nerve disorder comprising a compound represented by the general formula (I) : wherein R 1 is lower alkyl substituted with lower alkoxy, lower alkyl substituted with a heterocyclic group, a heterocyclic group, or a group represented by the formula (IIa): wherein R 4 is lower alkyl, R 5 is lower alkylene, and m is an integer of 1 to 6; R 2 is lower alkyl optionally substituted with phenyl; and R 3 is lower alkyl optionally substituted with halogen, lower alkoxy, or phenyl; condensed polycyclic hydrocarbon; or hydrogen.
IPC 8 full level
A61K 31/27 (2006.01); A61K 31/341 (2006.01); A61K 31/351 (2006.01); A61K 31/44 (2006.01); A61K 31/4402 (2006.01); A61K 31/77 (2006.01); A61P 25/02 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP US)
A61K 9/0019 (2013.01 - US); A61K 31/27 (2013.01 - EP US); A61K 31/341 (2013.01 - EP US); A61K 31/351 (2013.01 - EP US); A61K 31/44 (2013.01 - EP); A61K 31/4402 (2013.01 - EP US); A61K 31/77 (2013.01 - EP); A61P 25/02 (2017.12 - EP US); A61P 29/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (examination)
CHEN YI-FAN ET AL: "Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy", SCIENTIFIC REPORTS, vol. 7, no. 1, 28 March 2017 (2017-03-28), XP055923245, DOI: 10.1038/srep45366
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3466421 A1 20190410; EP 3466421 A4 20200101; EP 3466421 B1 20221130; JP 2022024055 A 20220208; JP 6989825 B2 20220112; JP 7297271 B2 20230626; JP WO2017204166 A1 20190322; US 11844776 B2 20231219; US 2019314320 A1 20191017; WO 2017204166 A1 20171130
DOCDB simple family (application)
EP 17802758 A 20170522; JP 2017019067 W 20170522; JP 2018519538 A 20170522; JP 2021184736 A 20211112; US 201716303629 A 20170522