EP 3478259 A4 20200226 - ASCORBIC ACID-AMINO ACID CONJUGATES AND THEIR USE IN REGULATION OF FLUID OUTFLOW
Title (en)
ASCORBIC ACID-AMINO ACID CONJUGATES AND THEIR USE IN REGULATION OF FLUID OUTFLOW
Title (de)
ASCORBINSÄURE-AMINOSÄURE-KONJUGATE UND DEREN VERWENDUNG BEI DER REGULIERUNG DES FLÜSSIGKEITSAUSFLUSSES
Title (fr)
CONJUGUÉS ACIDE ASCORBIQUE-ACIDE AMINÉ ET LEUR UTILISATION DANS LA RÉGULATION D'ÉCOULEMENT DE FLUIDE
Publication
Application
Priority
- US 201662356432 P 20160629
- US 2017039940 W 20170629
Abstract (en)
[origin: WO2018005762A2] Provided are ascorbic acid-amino acid conjugates and compositions for use in methods of lowering intraocular pressure and/or treating glaucoma by restoring the filtration capabilities of the endothelial lining of Schlemm's canal.
IPC 8 full level
A61K 8/64 (2006.01); A61K 8/67 (2006.01); A61K 31/341 (2006.01); A61K 31/4178 (2006.01); A61P 27/02 (2006.01); C07D 405/12 (2006.01); C07F 9/6584 (2006.01)
CPC (source: EP)
A61K 31/341 (2013.01); A61K 31/4178 (2013.01); A61K 47/551 (2017.07); A61P 27/02 (2017.12); C07D 307/62 (2013.01); C07D 405/12 (2013.01); C07K 5/06026 (2013.01); C07K 5/06052 (2013.01); C07K 5/0606 (2013.01); C07K 5/06078 (2013.01); C07K 5/06086 (2013.01); C07K 5/06095 (2013.01); C07K 5/06104 (2013.01); C07K 5/06113 (2013.01); C07K 5/06147 (2013.01); C07K 5/06156 (2013.01); C07K 5/0806 (2013.01); C07K 5/0808 (2013.01); C07K 5/081 (2013.01); C07K 5/0812 (2013.01); C07K 5/0817 (2013.01); C07K 5/0819 (2013.01); C07K 5/0821 (2013.01)
Citation (search report)
- [XP] WO 2016109457 A1 20160707 - ORANGE COUNTY GLAUCOMA [US]
- [A] WO 03018000 A1 20030306 - RATH MATTHIAS M D [US], et al
- [A] WO 03018003 A1 20030306 - RATH MATTHIAS [NL], et al
- [A] YUNG-HUN YANG ET AL: "Lipase catalyzed reaction of L-ascorbic acid with cinnamic acid esters and substituted cinnamic acids", BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, THE KOREAN SOCIETY FOR BIOTECHNOLOGY AND BIOENGINEERING, HEIDELBERG, vol. 17, no. 1, 1 February 2012 (2012-02-01), pages 50 - 54, XP035011564, ISSN: 1976-3816, DOI: 10.1007/S12257-011-0071-1
- See references of WO 2018005762A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2018005762 A2 20180104; WO 2018005762 A3 20180222; EP 3478259 A2 20190508; EP 3478259 A4 20200226
DOCDB simple family (application)
US 2017039940 W 20170629; EP 17821235 A 20170629