EP 3478843 A1 20190508 - OLIGONUCLEOTIDES COMPRISING MODIFIED NUCLEOSIDES
Title (en)
OLIGONUCLEOTIDES COMPRISING MODIFIED NUCLEOSIDES
Title (de)
OLIGONUKLEOTIDE MIT MODIFIZIERTEN NUKLEOSIDEN
Title (fr)
OLIGONUCLÉOTIDES COMPRENANT DES NUCLÉOSIDES MODIFIÉS
Publication
Application
Priority
- US 201662357623 P 20160701
- US 201662437592 P 20161221
- US 2017040299 W 20170630
Abstract (en)
[origin: WO2018005974A1] Polynucleotides, such as aptamers, comprising at least first one 5-position modified pyrimidine and at least one second 5-position modified pyrimidine are provided, wherein the first and second 5-position modified pyrimidines are different. Methods of selecting and using such polynucleotides, such as aptamers, are also provided.
IPC 8 full level
C12N 15/115 (2010.01); A61K 31/7115 (2006.01); C12N 15/11 (2006.01)
CPC (source: EP IL KR RU US)
A61P 3/06 (2018.01 - EP IL RU); A61P 9/10 (2018.01 - EP IL RU); C12N 15/1048 (2013.01 - IL RU US); C12N 15/111 (2013.01 - EP IL KR US); C12N 15/115 (2013.01 - EP IL KR US); C12Q 1/6804 (2013.01 - KR); C12Q 1/6876 (2013.01 - IL US); G01N 33/5308 (2013.01 - KR); C12N 2310/16 (2013.01 - EP IL KR US); C12N 2310/334 (2013.01 - EP IL KR US); C12N 2310/3341 (2013.01 - EP IL US); C12N 2310/335 (2013.01 - EP IL KR US); C12N 2330/31 (2013.01 - EP IL KR US); C12Q 2525/117 (2013.01 - KR); C12Q 2525/205 (2013.01 - KR)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2018005974 A1 20180104; WO 2018005974 A4 20180322; AU 2017290804 A1 20181220; AU 2017290804 B2 20240215; BR 112018075869 A2 20190402; BR 112018075869 A8 20221018; CA 3027626 A1 20180104; CN 109312346 A 20190205; DK 3478843 T3 20210830; EP 3478843 A1 20190508; EP 3478843 B1 20210804; EP 3913058 A1 20211124; ES 2886639 T3 20211220; IL 263852 A 20190131; IL 263852 B 20220601; IL 291931 A 20220601; IL 291931 B1 20240401; IL 311294 A 20240501; JP 2019527043 A 20190926; JP 2023036881 A 20230314; JP 7203613 B2 20230113; KR 102501963 B1 20230221; KR 20190024894 A 20190308; KR 20230031972 A 20230307; MX 2018014771 A 20190425; PL 3478843 T3 20220131; RU 2019102588 A 20200804; RU 2019102588 A3 20201130; RU 2021137915 A 20220204; RU 2763470 C2 20211229; SG 10201911369P A 20200130; SG 11201811199Q A 20190130; TW 201803992 A 20180201; TW I770036 B 20220711; US 10927380 B2 20210223; US 11578330 B2 20230214; US 2019177730 A1 20190613; US 2021171951 A1 20210610; US 2023313202 A1 20231005
DOCDB simple family (application)
US 2017040299 W 20170630; AU 2017290804 A 20170630; BR 112018075869 A 20170630; CA 3027626 A 20170630; CN 201780036021 A 20170630; DK 17740201 T 20170630; EP 17740201 A 20170630; EP 21174810 A 20170630; ES 17740201 T 20170630; IL 26385218 A 20181220; IL 29193122 A 20220404; IL 31129424 A 20240306; JP 2018566956 A 20170630; JP 2022209677 A 20221227; KR 20187036330 A 20170630; KR 20237005478 A 20170630; MX 2018014771 A 20170630; PL 17740201 T 20170630; RU 2019102588 A 20170630; RU 2021137915 A 20170630; SG 10201911369P A 20170630; SG 11201811199Q A 20170630; TW 106121878 A 20170630; US 201716307520 A 20170630; US 202017126330 A 20201218; US 202318153428 A 20230112