EP 3487295 B1 20201104 - PERFUSION LOOP ASSEMBLY FOR AN EX-VIVO LIVER PERFUSION
Title (en)
PERFUSION LOOP ASSEMBLY FOR AN EX-VIVO LIVER PERFUSION
Title (de)
PERFUSIONSKREISLAUFANORDNUNG FÜR EINE EX-VIVO-LEBERPERFUSION
Title (fr)
ENSEMBLE BOUCLE DE PERFUSION POUR UNE PERFUSION HÉPATIQUE EX VIVO
Publication
Application
Priority
- EP 16180837 A 20160722
- EP 2017068506 W 20170721
Abstract (en)
[origin: WO2018015548A2] - at least one pump (101), in particular only one pump (101) for providing a fluid flow of a perfusion fluid through a first branch line (110) and a second branch line (120); - the first branch line (110) being configured to provide a first portion of the perfusion fluid to the hepatic artery (111) (arteria hepatica propria or arteria hepatica communis) of the liver (13); the first branch line (110) being coupled with at least one first gas exchanger (112), in particular only one first gas exchanger (112), - the second branch line (120) being configured to provide a second portion of the perfusion fluid to the portal vein (121) (vena portae hepatis) of the liver; the second branch line (120) further comprising at least one first valve (122) for controlling the flow of the perfusion fluid into the portal vein (121) of the liver (13), - a liver chamber assembly (130) configured to hold the liver (13) ex vivo, - a liver outlet line (140) attached to the vena cava (142) (vena cava inferior) of the ex vivo liver (13), - at least one reservoir (150) connected to the liver outlet line (140) and upstream from the at least one pump (101).
IPC 8 full level
A01N 1/02 (2006.01)
CPC (source: EP US)
A01N 1/0247 (2013.01 - EP US)
Citation (opposition)
Opponent : Herrn Dr. Berndt Mayer
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- WO 2016090498 A1 20160616 - FREED DARREN [CA]
- US 2014017658 A1 20140116 - STEINMAN CHRISTOPHER P [US], et al
- US 7410474 B1 20080812 - FRIEND PETER [GB], et al
- EP 3459351 A1 20190327 - SCREEN HOLDINGS CO LTD [JP], et al
- WO 2014011547 A2 20140116 - LIFELINE SCIENT INC [US]
- US 5141847 A 19920825 - SUGIMACHI KEIZO [JP], et al
- DE 2603139 A1 19760819 - UCC UNION CHIMIQUE CONT
- EP 2133610 A1 20091216 - ASAHI BREWERIES LTD [JP], et al
- WO 2013068753 A1 20130516 - ORGANOX LTD [GB]
- CN 205124849 U 20160406 - THE 309TH HOSPITAL OF CHINESE PEOPLE'S LIBERATION ARMY
- EP 0702515 B1 19961227 - MAYER BERNDT [DE]
- S. OP DEN DRIES ET AL.: "Ex vivo Normothermic Machine Perfusion and Viability Testing of Discarded Human Donor Livers", AMERICAN JOURNAL OF TRANSPLANTATION, vol. 13, no. 5, 2013, pages 1327 - 1335, XP055424509
- BARBAS AS ET AL.: "Ex-vivo liver perfusion for organ preservation: Recent advances in the field", TRANSPLANTATION REVIEWS, vol. 30, no. 3, 2 May 2016 (2016-05-02), pages 154 - 160, XP029597331
- KATRIEN VEKEMANS ET AL.: "Artificial Circulation of the Liver: Machine Perfusion as a Preservation Method in Liver Transplantation", THE ANATOMICAL RECORD, vol. 291, no. 6, 2008, pages 735 - 740, XP055424859
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2018015548 A2 20180125; WO 2018015548 A3 20180301; CA 3031429 A1 20180125; CN 109688811 A 20190426; CN 109688811 B 20220603; EP 3487295 A2 20190529; EP 3487295 B1 20201104; ES 2842435 T3 20210714; JP 2019525776 A 20190912; US 11785938 B2 20231017; US 2020253194 A1 20200813
DOCDB simple family (application)
EP 2017068506 W 20170721; CA 3031429 A 20170721; CN 201780045177 A 20170721; EP 17751276 A 20170721; ES 17751276 T 20170721; JP 2019524519 A 20170721; US 201716319608 A 20170721