Global Patent Index - EP 3498822 A4

EP 3498822 A4 20200311 - METHOD FOR PRODUCING THREE-DIMENSIONAL STRUCTURE OF CELLS AND SYSTEM FOR PRODUCING THREE-DIMENSIONAL STRUCTURE

Title (en)

METHOD FOR PRODUCING THREE-DIMENSIONAL STRUCTURE OF CELLS AND SYSTEM FOR PRODUCING THREE-DIMENSIONAL STRUCTURE

Title (de)

VERFAHREN ZUR HERSTELLUNG DREIDIMENSIONALER ZELLSTRUKTUREN UND SYSTEM ZUR HERSTELLUNG EINER DREIDIMENSIONALEN STRUKTUR

Title (fr)

PROCÉDÉ DE PRODUCTION D'UNE STRUCTURE TRIDIMENSIONNELLE DE CELLULES ET SYSTÈME DE PRODUCTION DE STRUCTURE TRIDIMENSIONNELLE

Publication

EP 3498822 A4 20200311 (EN)

Application

EP 17839045 A 20170609

Priority

  • JP 2016158063 A 20160810
  • JP 2017021552 W 20170609

Abstract (en)

[origin: EP3498822A1] Proposed are a three-dimensional structuring method of cells and a three-dimensional structuring system of cells capable of efficiently bonding multiple cell clusters in a three-dimensional direction, pursuant to their growth, while ensuring safety. A plurality of fibers, in which one end of each of the fibers is held by a flat plate, are inserted together with the flat plate into a flow path through which a culture solution is supplied, a plurality of cell clusters are placed in the flow path upon causing the cell clusters to run with a liquid flow of the culture solution, and each of the cell clusters is cultured by being stacked on an outer surface of each of the fibers with the flat plate as a growth origin.

IPC 8 full level

C12N 5/00 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/34 (2006.01); C12M 1/36 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01); C12N 5/077 (2010.01)

CPC (source: EP US)

C12M 3/00 (2013.01 - US); C12M 21/08 (2013.01 - US); C12M 25/02 (2013.01 - EP US); C12M 25/10 (2013.01 - EP); C12M 25/12 (2013.01 - US); C12M 25/14 (2013.01 - EP); C12M 27/16 (2013.01 - US); C12M 29/10 (2013.01 - EP US); C12M 29/16 (2013.01 - US); C12M 41/14 (2013.01 - US); C12M 41/34 (2013.01 - US); C12M 41/44 (2013.01 - US); C12M 41/48 (2013.01 - US); C12N 5/00 (2013.01 - EP US); C12N 5/0062 (2013.01 - EP); C12N 5/0658 (2013.01 - EP US)

Citation (search report)

  • [X] EP 1078982 A2 20010228 - TOYO BOSEKI [JP], et al
  • [X] EP 1367119 A2 20031203 - TOYO BOSEKI [JP], et al
  • [X] LLOYD A. C. CHAPMAN ET AL: "Optimising Cell Aggregate Expansion in a Perfused Hollow Fibre Bioreactor via Mathematical Modelling", PLOS ONE, vol. 9, no. 8, 26 August 2014 (2014-08-26), pages e105813, XP055661891, DOI: 10.1371/journal.pone.0105813
  • [X] ILARIA ESTER DE NAPOLI ET AL: "Mesenchymal stem cell culture in convection-enhanced hollow fibre membrane bioreactors for bone tissue engineering", JOURNAL OF MEMBRANE SCIENCE, ELSEVIER BV, NL, vol. 379, no. 1, 1 June 2011 (2011-06-01), pages 341 - 352, XP028249699, ISSN: 0376-7388, [retrieved on 20110613], DOI: 10.1016/J.MEMSCI.2011.06.001
  • [T] BABA KAZUTOMO ET AL: "Development of biomimetic system for scale up of cell spheroids - building blocks for cell transplantation", 2017 39TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), IEEE, 11 July 2017 (2017-07-11), pages 1611 - 1616, XP033152311, DOI: 10.1109/EMBC.2017.8037147
  • See references of WO 2018029970A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

EP 3498822 A1 20190619; EP 3498822 A4 20200311; EP 3498822 B1 20211110; JP 6715330 B2 20200701; JP WO2018029970 A1 20190606; US 11746316 B2 20230905; US 2019169558 A1 20190606; WO 2018029970 A1 20180215

DOCDB simple family (application)

EP 17839045 A 20170609; JP 2017021552 W 20170609; JP 2018532850 A 20170609; US 201716324496 A 20170609