EP 3538151 A4 20200610 - HUMAN PLASMA-LIKE MEDIUM
Title (en)
HUMAN PLASMA-LIKE MEDIUM
Title (de)
HUMANPLASMAÄHNLICHES MEDIUM
Title (fr)
MILIEU DE TYPE PLASMA HUMAIN
Publication
Application
Priority
- US 201662421074 P 20161111
- US 2017061377 W 20171113
Abstract (en)
[origin: WO2018089928A1] In some aspects, described herein are cell culture media that are useful for in vitro culture of mammalian cells. The culture media contain a variety of small organic compounds that are found in normal adult human blood. Also described are methods of using the culture media for a variety of purposes. Also described are methods of treating cancer.
IPC 8 full level
A61K 39/395 (2006.01); A61P 19/06 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 1/00 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C12N 5/00 (2006.01)
CPC (source: EP US)
A61P 19/06 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 1/00 (2013.01 - EP); C12N 5/0018 (2013.01 - EP US); C12M 41/32 (2013.01 - US); C12N 2500/32 (2013.01 - EP US); C12N 2500/33 (2013.01 - EP); C12N 2500/34 (2013.01 - EP US); C12N 2500/38 (2013.01 - EP US)
Citation (search report)
- [Y] US 2012258439 A1 20121011 - ALI BIN M ABDULLAH JAFFAR [MY]
- [Y] SANGKOP FEBBIE ET AL: "Uric acid: a modulator of prostate cells and activin sensitivity", MOLECULAR AND CELLULAR BIOCHEMISTRY, NORWELL, MA, US, vol. 414, no. 1, 24 February 2016 (2016-02-24), pages 187 - 199, XP035923047, ISSN: 0300-8177, [retrieved on 20160224], DOI: 10.1007/S11010-016-2671-8
- [Y] NISHIDA Y ET AL: "Effect of free radicals on lymphocyte response to mitogens and rosette formation", CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, SAN DIEGO, CA, US, vol. 19, no. 3, 1 June 1981 (1981-06-01), pages 319 - 324, XP026198218, ISSN: 0090-1229, [retrieved on 19810601], DOI: 10.1016/0090-1229(81)90074-X
- [YD] NIKOLAOS PSYCHOGIOS ET AL: "The Human Serum Metabolome", PLOS ONE, 16 February 2011 (2011-02-16), Online, pages 1 - 23, XP055274573, Retrieved from the Internet <URL:http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016957> [retrieved on 20160523], DOI: 10.1371/journal.pone.0016957
- [XP] CANTOR JASON R ET AL: "Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase", CELL, ELSEVIER, AMSTERDAM, NL, vol. 169, no. 2, 6 April 2017 (2017-04-06), pages 258, XP029970790, ISSN: 0092-8674, DOI: 10.1016/J.CELL.2017.03.023
- [T] JOHAN VANDE VOORDE ET AL: "Improving the metabolic fidelity of cancer models with a physiological cell culture medium", SCIENCE ADVANCES, vol. 5, no. 1, 1 January 2019 (2019-01-01), pages eaau7314, XP055690553, DOI: 10.1126/sciadv.aau7314
- See also references of WO 2018089928A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2018089928 A1 20180517; CA 3043640 A1 20180517; CN 110121359 A 20190813; EP 3538151 A1 20190918; EP 3538151 A4 20200610; EP 3538151 B1 20240626; JP 2020501522 A 20200123; JP 7406990 B2 20231228; US 11453858 B2 20220927; US 2019352598 A1 20191121; US 2023051644 A1 20230216
DOCDB simple family (application)
US 2017061377 W 20171113; CA 3043640 A 20171113; CN 201780081328 A 20171113; EP 17869135 A 20171113; JP 2019524430 A 20171113; US 201716348402 A 20171113; US 202217881200 A 20220804