EP 3554531 A1 20191023 - TREATMENT OF AGE-RELATED DEGENERATION AND OTHER EYE DISEASES WITH APOLIPOPROTEIN MIMETICS
Title (en)
TREATMENT OF AGE-RELATED DEGENERATION AND OTHER EYE DISEASES WITH APOLIPOPROTEIN MIMETICS
Title (de)
BEHANDLUNG VON ALTERSBEDINGTER DEGENERATION UND ANDEREN AUGENKRANKHEITEN MIT APOLIPOPROTEINMIMETIKA
Title (fr)
TRAITEMENT DE LA DÉGÉNÉRESCENCE LIÉE À L'ÂGE ET D'AUTRES MALADIES OCULAIRES AVEC DES MIMÉTIQUES D'APOLIPOPROTÉINE
Publication
Application
Priority
US 2017014754 W 20170124
Abstract (en)
[origin: WO2018139991A1] The present disclosure provides apolipoprotein (apo) mimetics useful for the treatment of age- related macular degeneration (AMD) and other eye disorders. The apo mimetics can be peptides/polypeptides that mimic, e.g., the lipid-clearing action of apolipoproteins such as apoA-I and apoE, The apo mimetics can exert other beneficial effects, such as reduction of inflammation, oxidative stress and neovascularization. The apo mimetics can be used to treat any stages (including the early, intermediate and advance stages) of AMD, and any phenotypes of AMD, including geographic atrophy (GA) (including non-central GA and central GA) and neovascularization (NV) (including types 1, 2 and 3 NV). The apo mimetics can be used alone or in conjunction with other therapeutic agents, such as a complement: inhibitor and/or an anti-angiogenic agent, to treat AMD, including atrophic AMD and neovascular AMD, and other eye disorders.
IPC 8 full level
A61K 38/17 (2006.01); A61P 27/02 (2006.01)
CPC (source: EP KR)
A61K 9/0019 (2013.01 - KR); A61K 9/0048 (2013.01 - KR); A61K 38/17 (2013.01 - EP KR); A61K 45/06 (2013.01 - KR); A61P 27/02 (2017.12 - EP KR); A61K 2039/505 (2013.01 - KR); A61K 2039/54 (2013.01 - KR); A61K 2039/545 (2013.01 - KR)
Citation (search report)
See references of WO 2018139991A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2018139991 A1 20180802; CN 110545836 A 20191206; EP 3554531 A1 20191023; JP 2020514407 A 20200521; KR 20190124704 A 20191105
DOCDB simple family (application)
US 2017014754 W 20170124; CN 201780087274 A 20170124; EP 17703587 A 20170124; JP 2019560039 A 20170124; KR 20197021355 A 20170124