EP 3554544 A4 20200729 - ANTI-CUB DOMAIN-CONTAINING PROTEIN 1 (CDCP1) ANTIBODIES, ANTIBODY DRUG CONJUGATES, AND METHODS OF USE THEREOF
Title (en)
ANTI-CUB DOMAIN-CONTAINING PROTEIN 1 (CDCP1) ANTIBODIES, ANTIBODY DRUG CONJUGATES, AND METHODS OF USE THEREOF
Title (de)
ANTI-CUB-HALTIGE PROTEIN 1-(CDCP1)-ANTIKÖRPER, ANTIKÖRPER-WIRKSTOFF-KONJUGATE UND VERFAHREN ZUR VERWENDUNG DAVON
Title (fr)
ANTICORPS ANTI-PROTÉINE 1 CONTENANT UN DOMAINE ANTI-CUB (CDCP1), CONJUGUÉS ANTICORPS-MÉDICAMENT ET LEURS MÉTHODES D'UTILISATION
Publication
Application
Priority
- US 201662435509 P 20161216
- US 201762488445 P 20170421
- US 201762588516 P 20171120
- US 2017066661 W 20171215
Abstract (en)
[origin: WO2018112334A1] This disclosure relates to anti-cancer antibodies and methods of treatment, detection, and diagnosis using the same.
IPC 8 full level
A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01)
CPC (source: EP US)
A61K 47/65 (2017.08 - US); A61K 47/68031 (2023.08 - EP US); A61K 47/68035 (2023.08 - EP US); A61K 47/6849 (2017.08 - EP US); A61P 35/00 (2018.01 - EP US); C07K 16/2896 (2013.01 - EP); C07K 16/30 (2013.01 - US); A61K 45/06 (2013.01 - US); A61K 2039/505 (2013.01 - EP US); C07K 2317/21 (2013.01 - EP); C07K 2317/24 (2013.01 - EP); C07K 2317/33 (2013.01 - EP); C07K 2317/732 (2013.01 - EP); C07K 2317/76 (2013.01 - EP); C07K 2317/77 (2013.01 - EP); C07K 2317/92 (2013.01 - EP)
Citation (search report)
- [XI] WO 2015082446 A1 20150611 - HOFFMANN LA ROCHE [CH], et al
- [XI] WO 2011023390 A1 20110303 - HOFFMANN LA ROCHE [CH], et al
- [XI] WO 2008133851 A1 20081106 - ALEXION PHARMA INC [US], et al
- [XI] KEISUKE FUKUCHI ET AL: "Inhibition of Tumor Metastasis: Functional Immune Modulation of the CUB Domain Containing Protein 1", MOLECULAR PHARMACEUTICS, vol. 7, no. 1, 16 February 2010 (2010-02-16), US, pages 245 - 253, XP055704816, ISSN: 1543-8384, DOI: 10.1021/mp900236t
- [I] KOLLMORGEN GWENDLYN ET AL: "Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy", MOLECULAR ONCOLOGY, vol. 7, no. 6, 3 September 2013 (2013-09-03), pages 1142 - 1151, XP028778420, ISSN: 1574-7891, DOI: 10.1016/J.MOLONC.2013.08.009
- [I] SIVA AMARA C ET AL: "Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 68, no. 10, 15 May 2008 (2008-05-15), pages 3759 - 3766, XP002559247, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-07-1657
- See also references of WO 2018112334A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2018112334 A1 20180621; CA 3047115 A1 20180621; CN 110234348 A 20190913; CN 110234348 B 20240625; EP 3554544 A1 20191023; EP 3554544 A4 20200729; JP 2020502271 A 20200123; JP 2022101693 A 20220706; JP 2024026234 A 20240228; JP 7350313 B2 20230926; JP 7401126 B2 20231219; MA 50134 A 20200729; US 11702481 B2 20230718; US 2020181281 A1 20200611; US 2024084032 A1 20240314
DOCDB simple family (application)
US 2017066661 W 20171215; CA 3047115 A 20171215; CN 201780077883 A 20171215; EP 17880084 A 20171215; JP 2019553163 A 20171215; JP 2022075922 A 20220502; JP 2023203139 A 20231130; MA 50134 A 20171215; US 201716469197 A 20171215; US 202318320885 A 20230519