EP 3556775 B1 20211117 - ANTI-LAG-3 ANTIBODIES TO TREAT HEMATOLOGICAL MALIGNANCIES
Title (en)
ANTI-LAG-3 ANTIBODIES TO TREAT HEMATOLOGICAL MALIGNANCIES
Title (de)
ANTI-LAG-3-ANTIKÖRPER ZUR BEHANDLUNG VON HÄMATOLOGISCHEN MALIGNOMEN
Title (fr)
ANTICORPS ANTI-LAG-3 POUR TRAITER DES MALIGNITÉS HÉMATOLOGIQUES
Publication
Application
Priority
- US 201461932589 P 20140128
- EP 15705137 A 20150126
- US 2015012916 W 20150126
Abstract (en)
[origin: WO2015116539A1] Provided are methods for clinical treatment of hematological malignancies, such as relapsed or refractory chronic lymphocytic leukemia or lymphoma using an anti-LAG-3 antibody. Particular malignancies include, e.g., chronic lymphocytic leukemia (CLL), Hodgkin lymphoma (HL), or non-Hodgkin lymphoma (NHL).
IPC 8 full level
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01)
CPC (source: CN EP KR US)
A61P 35/00 (2018.01 - EP KR); A61P 35/02 (2018.01 - EP); A61P 35/04 (2018.01 - EP); A61P 37/04 (2018.01 - EP); C07K 16/2803 (2013.01 - CN EP KR US); A61K 2039/505 (2013.01 - CN EP KR US); A61K 2039/545 (2013.01 - US); C07K 2317/21 (2013.01 - CN EP US); C07K 2317/53 (2013.01 - US); C07K 2317/56 (2013.01 - CN); C07K 2317/565 (2013.01 - CN); C07K 2317/71 (2013.01 - US); C07K 2317/73 (2013.01 - KR); C07K 2317/75 (2013.01 - US); C07K 2317/92 (2013.01 - CN EP US)
Citation (examination)
LIPSON: "Initial experience administering BMS-986016, a monoclonalantibody that targets lymphocyte activation gene (LAG)-3, aloneand in combination with nivolumab to patients with hematologicand solid malignancies", JOURNAL FOR IMMUNOTHERAPY OF CANCER, vol. 4, no. 1, P232, 16 November 2016 (2016-11-16), pages 129 - 130, XP021241441
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2015116539 A1 20150806; BR 112016017174 A2 20171003; CA 2937503 A1 20150806; CN 105992595 A 20161005; CY 1124977 T1 20221125; DK 3556775 T3 20220103; EA 201691361 A1 20161230; EP 3099716 A1 20161207; EP 3556775 A1 20191023; EP 3556775 B1 20211117; EP 3988572 A1 20220427; ES 2902369 T3 20220328; HR P20212033 T1 20220401; HU E057817 T2 20220628; JP 2017505773 A 20170223; JP 2020015737 A 20200130; JP 2022068355 A 20220509; KR 20160106762 A 20160912; KR 20220147714 A 20221103; LT 3556775 T 20220125; MX 2016009010 A 20170118; MX 2022007800 A 20220719; PL 3556775 T3 20220131; PT 3556775 T 20211231; RS 62788 B1 20220228; SI 3556775 T1 20220228; US 2016326248 A1 20161110; US 2018244773 A1 20180830; US 2021122820 A1 20210429; US 2024150459 A1 20240509
DOCDB simple family (application)
US 2015012916 W 20150126; BR 112016017174 A 20150126; CA 2937503 A 20150126; CN 201580006297 A 20150126; CY 221100044 T 20220118; DK 19161885 T 20150126; EA 201691361 A 20150126; EP 15705137 A 20150126; EP 19161885 A 20150126; EP 21201919 A 20150126; ES 19161885 T 20150126; HR P20212033 T 20150126; HU E19161885 A 20150126; JP 2016548710 A 20150126; JP 2019151663 A 20190822; JP 2022027920 A 20220225; KR 20167023120 A 20150126; KR 20227036733 A 20150126; LT 19161885 T 20150126; MX 2016009010 A 20150126; MX 2022007800 A 20160708; PL 19161885 T 20150126; PT 19161885 T 20150126; RS P20211606 A 20150126; SI 201531761 T 20150126; US 201515108729 A 20150126; US 201815893102 A 20180209; US 202017016092 A 20200909; US 202318227636 A 20230728