EP 3558272 A1 20191030 - ORAL PHARMACEUTICAL COMPOSITION WITH IMPROVED TASTE-MASKING PROPERTIES
Title (en)
ORAL PHARMACEUTICAL COMPOSITION WITH IMPROVED TASTE-MASKING PROPERTIES
Title (de)
ORALE PHARMAZEUTISCHE ZUSAMMENSETZUNG MIT VERBESSERTEN GESCHMACKSMASKIERENDEN EIGENSCHAFTEN
Title (fr)
COMPOSITION PHARMACEUTIQUE ORALE PRÉSENTANT DES PROPRIÉTÉS DE MASQUAGE DU GOÛT AMÉLIORÉES
Publication
Application
Priority
- EP 16206837 A 20161223
- EP 2017083831 W 20171220
Abstract (en)
[origin: WO2018115130A1] The invention provides a pharmaceutical composition for the taste-masking of poorly soluble drug substances wherein a melt of a poorly tasting drug is sorbed by water- dispersible, at least partially hydrophilic polymeric carrier particles. Prior to oral consumption, these drug-melt-treated polymeric carrier particles can be dispersed easily in water, yielding a drink suspension with a neutral taste. Alternatively, the drug-melt-treated polymeric carrier particles may be mixed with further excipients such as sugars, sweeteners or flavourants to provide a dosage form which upon dispersion lends a pleasant taste to the aqueous dispersion medium. The invention further provides an improved process for the preparation of these taste-masked compositions and dosage forms, for instance in heatable vacuum granulators.
IPC 8 full level
A61K 9/16 (2006.01); A61K 31/192 (2006.01); A61K 31/223 (2006.01)
CPC (source: EP)
A61K 9/1652 (2013.01); A61K 31/192 (2013.01); A61K 31/223 (2013.01)
Citation (search report)
See references of WO 2018115130A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
EP 2017083831 W 20171220; EP 17825506 A 20171220