EP 3573965 B1 20210623 - INDANYLAMINOPYRAZINYLCYCLOPROPANECARBOXYLIC ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
Title (en)
INDANYLAMINOPYRAZINYLCYCLOPROPANECARBOXYLIC ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
Title (de)
INDANYLAMINOPYRAZOLYLCYCLOPROPANCARBONSÄUREN, PHARMAZEUTISCHE ZUSAMMENSETZUNGEN UND VERWENDUNGEN DAVON
Title (fr)
ACIDES INDANYLAMINOPYRAZINYLCYCLOPROPANECARBOXYLIQUES, COMPOSITIONS PHARMACEUTIQUES ET LEURS UTILISATIONS
Publication
Application
Priority
- EP 17153381 A 20170126
- EP 2018051383 W 20180122
Abstract (en)
[origin: US2018208560A1] wherein the groups R, R1, R2, R3, m and n are defined herein, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
IPC 8 full level
C07D 401/10 (2006.01); A61K 31/4965 (2006.01); A61K 31/497 (2006.01); A61P 3/10 (2006.01); C07D 241/20 (2006.01); C07D 403/10 (2006.01); C07D 405/10 (2006.01); C07D 409/10 (2006.01); C07D 413/10 (2006.01); C07D 417/10 (2006.01)
CPC (source: EP US)
A61K 31/4965 (2013.01 - US); A61K 31/497 (2013.01 - US); A61K 45/06 (2013.01 - EP US); A61P 3/04 (2017.12 - EP US); A61P 3/06 (2017.12 - EP US); A61P 3/10 (2017.12 - EP US); A61P 9/00 (2017.12 - EP US); C07D 241/20 (2013.01 - EP US); C07D 401/10 (2013.01 - EP US); C07D 403/10 (2013.01 - EP US); C07D 403/12 (2013.01 - EP US); C07D 405/10 (2013.01 - EP US); C07D 409/10 (2013.01 - EP US); C07D 413/10 (2013.01 - EP US); C07D 417/10 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 10253004 B2 20190409; US 2018208560 A1 20180726; AR 110777 A1 20190502; CN 110214135 A 20190906; CN 110214135 B 20230221; EP 3573965 A1 20191204; EP 3573965 B1 20210623; JP 2020505394 A 20200220; JP 6968181 B2 20211117; TW 201840541 A 20181116; WO 2018138026 A1 20180802
DOCDB simple family (application)
US 201815876237 A 20180122; AR P180100172 A 20180125; CN 201880007924 A 20180122; EP 18703219 A 20180122; EP 2018051383 W 20180122; JP 2019540033 A 20180122; TW 107102700 A 20180125