EP 3578202 A1 20191211 - A TOPOISOMERASE INHIBITOR FOR MIMICKING THE EFFECT OF IONIZING RADIATIONS ON T CELLS
Title (en)
A TOPOISOMERASE INHIBITOR FOR MIMICKING THE EFFECT OF IONIZING RADIATIONS ON T CELLS
Title (de)
TOPOISOMERASE-INHIBITOREN ZUR NACHAHMUNG DER WIRKUNG VON IONISIERENDEN STRAHLUNGEN AUF T-ZELLEN
Title (fr)
INHIBITEUR DE TOPOISOMÉRASE PERMETTANT DE REPRODUIRE L'EFFET DE RAYONNEMENTS IONISANTS SUR DES LYMPHOCYTES T
Publication
Application
Priority
EP 18305699 A 20180608
Abstract (en)
The present invention relates to a method for mimicking the effects of ionizing radiations on cells, wherein cells are contacted with a topoisomerase inhibitor.
IPC 8 full level
A61K 45/00 (2006.01); A61K 31/335 (2006.01); A61K 31/357 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP US)
A61K 31/05 (2013.01 - US); A61K 31/335 (2013.01 - EP); A61K 31/352 (2013.01 - US); A61K 31/357 (2013.01 - EP); A61K 31/704 (2013.01 - US); A61K 31/7048 (2013.01 - US); A61K 45/00 (2013.01 - EP); A61K 47/6809 (2017.07 - US); C12Q 1/25 (2013.01 - US); G01N 33/5008 (2013.01 - US); G01N 33/5011 (2013.01 - US); G01N 33/505 (2013.01 - US); G01N 33/56966 (2013.01 - US); G01N 33/573 (2013.01 - US); C12Q 2521/519 (2013.01 - US); G01N 2800/40 (2013.01 - US)
Citation (search report)
- [A] WO 2014154854 A1 20141002 - CTRE HOSP UNIVERSITAIRE DE MONTPELLIER [FR], et al
- [A] WO 2018041960 A1 20180308 - INST REGIONAL CANCER MONTPELLIER [FR]
- [A] GILLIAN C BARNETT ET AL: "Standardized Total Average Toxicity Score: A Scale- and Grade-Independent Measure of Late Radiotherapy Toxicity to Facilitate Pooling of Data From Different Studies", INTERNATIONAL JOURNAL OF RADIATION: ONCOLOGY BIOLOGY PHYSICS, PERGAMON PRESS, USA, vol. 82, no. 3, 18 March 2011 (2011-03-18), pages 1065 - 1074, XP028453122, ISSN: 0360-3016, [retrieved on 20110415], DOI: 10.1016/J.IJROBP.2011.03.015
- [A] DAVID AZRIA ET AL: "Radiation-induced CD8 T-lymphocyte Apoptosis as a Predictor of Breast Fibrosis After Radiotherapy: Results of the Prospective Multicenter French Trial", EBIOMEDICINE, vol. 2, no. 12, 7 November 2015 (2015-11-07), pages 1965 - 1973, XP055324418, ISSN: 2352-3964, DOI: 10.1016/j.ebiom.2015.10.024
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 3578202 A1 20191211; EP 3801622 A1 20210414; EP 3801622 B1 20220831; US 2021220381 A1 20210722; WO 2019234227 A1 20191212
DOCDB simple family (application)
EP 18305699 A 20180608; EP 19731184 A 20190607; EP 2019064969 W 20190607; US 201915734319 A 20190607