EP 3587419 A4 20200805 - FGFR INHIBITOR AND APPLICATION THEREOF
Title (en)
FGFR INHIBITOR AND APPLICATION THEREOF
Title (de)
FGFR-INHIBITOR UND ANWENDUNG DAVON
Title (fr)
INHIBITEUR DE FGFR ET SON APPLICATION
Publication
Application
Priority
- CN 2017074967 W 20170227
- CN 2018077314 W 20180227
Abstract (en)
[origin: EP3587419A1] An azatricyclic compound (as represented by formula I) which acts as an inhibitor of fibroblast growth factor receptors (FGFR), as well as a pharmaceutical composition thereof, a preparation method, and a use therefor in the treatment of FGFR-mediated diseases. The azatricyclic compound exerts an effect by means of participating in the regulation of a plurality of processes such as cell proliferation, apoptosis, migration, neovascularization, and the like. AA%%%Formula (I).
IPC 8 full level
C07D 471/14 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); A61K 31/4985 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01)
CPC (source: EP KR RU US)
A61K 31/437 (2013.01 - RU); A61K 31/4375 (2013.01 - RU); A61K 31/4985 (2013.01 - RU); A61K 31/519 (2013.01 - KR RU); A61K 31/5377 (2013.01 - KR); A61P 35/00 (2017.12 - EP KR RU US); C07D 471/14 (2013.01 - EP KR RU US); C07D 487/14 (2013.01 - RU); C07D 519/00 (2013.01 - EP KR RU US)
Citation (search report)
- [XAI] WO 03082871 A1 20031009 - HOFFMANN LA ROCHE [CH]
- See references of WO 2018153373A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3587419 A1 20200101; EP 3587419 A4 20200805; AU 2018226315 A1 20191003; AU 2018226315 B2 20210128; CA 3054455 A1 20180830; CA 3054455 C 20211026; CN 110382499 A 20191025; CN 110382499 B 20230103; JP 2020509089 A 20200326; JP 6876833 B2 20210526; KR 20190126344 A 20191111; RU 2745035 C1 20210318; SG 11201907909T A 20190927; TW 201831483 A 20180901; TW I741155 B 20211001; US 11365196 B2 20220621; US 2021130353 A1 20210506; WO 2018153373 A1 20180830
DOCDB simple family (application)
EP 18757942 A 20180227; AU 2018226315 A 20180227; CA 3054455 A 20180227; CN 2018077314 W 20180227; CN 201880013847 A 20180227; JP 2019567775 A 20180227; KR 20197028565 A 20180227; RU 2019129669 A 20180227; SG 11201907909T A 20180227; TW 107106654 A 20180227; US 201816488899 A 20180227