EP 3600265 A1 20200205 - METHOD OF TREATMENT AND DEVICE FOR THE IMPROVED BIOAVAILABILITY OF LEUKOTRIENE RECEPTOR ANTAGONISTS
Title (en)
METHOD OF TREATMENT AND DEVICE FOR THE IMPROVED BIOAVAILABILITY OF LEUKOTRIENE RECEPTOR ANTAGONISTS
Title (de)
BEHANDLUNGSVERFAHREN UND VORRICHTUNG ZUR VERBESSERTEN BIOVERFÜGBARKEIT VON LEUKOTRIENREZEPTORANTAGONISTEN
Title (fr)
MÉTHODE DE TRAITEMENT ET DISPOSITIF POUR LA BIODISPONIBILITÉ AMÉLIORÉE D'ANTAGONISTES DES RÉCEPTEURS DES LEUCOTRIÈNES
Publication
Application
Priority
- US 201762478876 P 20170330
- CA 2018050389 W 20180329
Abstract (en)
[origin: WO2018176149A1] Disclosed is a method of administration and device for the improved bioavailability of leukotriene receptor antagonists. This method and device involve an alkaline surface pH oral film dosage form designed to deliver leukotriene receptor antagonists, such as Montelukast, to the stomach in an amorphous precipitate suspended in aqueous medium. Also disclosed is a device and method for treating a disease, such as a neurodegenerative disease or condition associated with neuroinflammation induced by a leukotriene. The device is a film unit dosage form having an alkaline surface pH film layer and a safe and effective amount of Montelukast. The device is configured and formulated to predominantly achieve enteral delivery of the Montelukast. The method includes enterally delivering to a human or an animal in need of treatment, a safe and effective amount of Montelukast capable of crossing the blood-brain barrier.
IPC 8 full level
A61K 9/70 (2006.01); A61K 31/47 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); C07D 215/18 (2006.01)
CPC (source: EP KR)
A61K 9/006 (2013.01 - EP KR); A61K 9/7007 (2013.01 - KR); A61K 31/47 (2013.01 - EP KR); A61K 47/14 (2013.01 - KR); A61K 47/183 (2013.01 - KR); A61P 25/28 (2017.12 - EP KR); A61P 29/00 (2017.12 - EP KR); C07D 215/18 (2013.01 - EP); A61K 47/183 (2013.01 - EP)
Citation (search report)
See references of WO 2018176149A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2018176149 A1 20181004; AU 2018241534 A1 20190926; BR 112019018388 A2 20200407; CA 3056944 A1 20181004; CN 110381931 A 20191025; EP 3600265 A1 20200205; JP 2020512309 A 20200423; KR 20190128637 A 20191118; MX 2019010573 A 20191024
DOCDB simple family (application)
CA 2018050389 W 20180329; AU 2018241534 A 20180329; BR 112019018388 A 20180329; CA 3056944 A 20180329; CN 201880016281 A 20180329; EP 18774366 A 20180329; JP 2019548270 A 20180329; KR 20197025967 A 20180329; MX 2019010573 A 20180329