EP 3609885 A1 20200219 - BIOCOMPATIBLE MODULAR TETRAZINE PLATFORM
Title (en)
BIOCOMPATIBLE MODULAR TETRAZINE PLATFORM
Title (de)
BIOKOMPATIBLE MODULARE TETRAZIN-PLATTFORM
Title (fr)
PLATEFORME TÉTRAZINE MODULAIRE BIOCOMPATIBLE
Publication
Application
Priority
- FR 1752451 A 20170324
- FR 1759851 A 20171019
- EP 2018057520 W 20180323
Abstract (en)
[origin: WO2018172543A1] The invention relates to a trifunctionalised platform of formula (I), to the use thereof as a diagnostic or theragnostic agent and/or a medicament, and to a method for synthesis by the inverse electron demand Diels-Alder reaction from a bifunctionalised tetrazine of formula (II) that itself can be obtained from a monofunctionalised tetrazine of formula (IV). The invention also relates to the monofunctionalised and bifunctionalised tetrazine synthesis intermediates of formulae (IV) and (II) respectively.
IPC 8 full level
C07D 403/12 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07F 5/02 (2006.01); C07K 7/06 (2006.01)
CPC (source: EP US)
A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 403/12 (2013.01 - EP US); C07D 403/14 (2013.01 - EP US); C07D 405/12 (2013.01 - US); C07D 405/14 (2013.01 - EP); C07F 5/022 (2013.01 - EP US); C07K 7/06 (2013.01 - EP)
Citation (search report)
See references of WO 2018172543A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2018172543 A1 20180927; CN 110573502 A 20191213; CN 110573502 B 20230718; EP 3609885 A1 20200219; JP 2020512329 A 20200423; JP 7191034 B2 20221216; US 11242359 B2 20220208; US 2020354381 A1 20201112
DOCDB simple family (application)
EP 2018057520 W 20180323; CN 201880020928 A 20180323; EP 18711598 A 20180323; JP 2019552066 A 20180323; US 201816496387 A 20180323