EP 3610010 A4 20210224 - COMPLEMENT FACTOR D ANTAGONIST ANTIBODIES AND CONJUGATES THEREOF
Title (en)
COMPLEMENT FACTOR D ANTAGONIST ANTIBODIES AND CONJUGATES THEREOF
Title (de)
KOMPLEMENTFAKTOR-D-ANTAGONISTEN-ANTIKÖRPER UND KONJUGATE DAVON
Title (fr)
ANTICORPS ANTAGONISTES DU FACTEUR D DU COMPLÉMENT ET LEURS CONJUGUÉS
Publication
Application
Priority
- US 201762485718 P 20170414
- US 2018027378 W 20180412
Abstract (en)
[origin: WO2018191548A2] The present invention provides antagonizing antibodies that bind to complement factor D (CFD), conjugates thereof, and methods of using same. The anti-CFD antibodies can be used therapeutically alone or in combination with other therapeutics to treat age related macular degeneration and other diseases.
IPC 8 full level
C07K 16/18 (2006.01); A61P 27/02 (2006.01); A61P 37/06 (2006.01); C12N 9/64 (2006.01)
CPC (source: EP US)
A61K 47/6843 (2017.07 - EP US); A61K 47/6885 (2017.07 - EP US); C07K 16/18 (2013.01 - EP US); C07K 16/40 (2013.01 - US); A61P 27/02 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C07K 14/472 (2013.01 - US); C07K 2317/24 (2013.01 - EP US); C07K 2317/33 (2013.01 - EP US); C07K 2317/34 (2013.01 - EP US); C07K 2317/41 (2013.01 - EP US); C07K 2317/51 (2013.01 - US); C07K 2317/515 (2013.01 - US); C07K 2317/55 (2013.01 - EP US); C07K 2317/565 (2013.01 - EP US); C07K 2317/734 (2013.01 - EP US); C07K 2317/76 (2013.01 - EP US); C07K 2317/92 (2013.01 - EP US); C07K 2317/94 (2013.01 - EP US); C12Y 304/21046 (2013.01 - US)
Citation (search report)
- [XYI] WO 2015168468 A1 20151105 - GENENTECH INC [US], et al
- [XYI] WO 2008055206 A2 20080508 - GENENTECH INC [US], et al
- [XYI] WO 2009134711 A1 20091105 - GENENTECH INC [US], et al
- [XYI] WO 2011057014 A1 20110512 - GENENTECH INC [US], et al
- [XYI] WO 9942133 A1 19990826 - TANOX INC [US]
- [Y] WO 2012145746 A1 20121026 - UNIV COLORADO REGENTS [US], et al
- [XP] WO 2017075173 A2 20170504 - GENENTECH INC [US], et al
- [IP] CN 106905431 A 20170630 - XUHUA (SHANGHAI) BIOLOGICAL RES AND DEV CENTER CO LTD
- [IP] WO 2017129064 A1 20170803 - CHENGDU KANGHONG BIOTECHNOLOGIES CO LTD [CN]
- [A] "RecName: Full=Complement factor D; EC=3.4.21.46; AltName: Full=Adipsin; AltName: Full=C3 convertase activator; AltName: Full=Properdin factor D; Flags: Precursor", UNIPROT, 21 July 1986 (1986-07-21), XP002614847
- [Y] MAISIE J. JORALEMON ET AL: "PEGylated polymers for medicine: from conjugation to self-assembled systems", CHEMICAL COMMUNICATIONS, vol. 46, no. 9, 1 January 2010 (2010-01-01), pages 1377, XP055760126, ISSN: 1359-7345, DOI: 10.1039/b920570p
- See references of WO 2018191548A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2018191548 A2 20181018; WO 2018191548 A3 20181122; AU 2018250695 A1 20191107; AU 2022201163 A1 20220317; CA 3059938 A1 20181018; EP 3610010 A2 20200219; EP 3610010 A4 20210224; US 11584790 B2 20230221; US 2018334496 A1 20181122; US 2023382983 A1 20231130
DOCDB simple family (application)
US 2018027378 W 20180412; AU 2018250695 A 20180412; AU 2022201163 A 20220221; CA 3059938 A 20180412; EP 18784891 A 20180412; US 201815952092 A 20180412; US 202318165233 A 20230206