EP 3612211 A4 20210217 - GUT-PROTECTIVE EFFECT OF RIG-I/MAVS AND STING ACTIVATION
Title (en)
GUT-PROTECTIVE EFFECT OF RIG-I/MAVS AND STING ACTIVATION
Title (de)
DARMSCHÜTZENDE WIRKUNG DER RIG-I/MAVS- UND STING-AKTIVIERUNG
Title (fr)
EFFET PROTECTEUR DE L'INTESTIN OBTENU PAR L'ACTIVATION DE RIG-I/MAVS ET DE STING
Publication
Application
Priority
- US 201762486213 P 20170417
- US 201762589845 P 20171122
- US 2018027961 W 20180417
Abstract (en)
[origin: WO2018195070A1] Disclosed herein are methods for inhibiting irradiation- and chemo-induced impact on intestinal barrier function and graft versus host disease following allogeneic hematopoietic stem cell transplantation by targeting the RIG-I or STING signaling pathways.
IPC 8 full level
A61K 38/20 (2006.01); A61K 31/352 (2006.01); A61K 31/429 (2006.01); A61K 31/661 (2006.01); A61K 31/7084 (2006.01); A61K 31/7088 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 35/76 (2015.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01); A61P 37/02 (2006.01); A61P 43/00 (2006.01); C07K 14/54 (2006.01)
CPC (source: EP US)
A61K 31/352 (2013.01 - EP); A61K 31/429 (2013.01 - EP); A61K 31/661 (2013.01 - EP); A61K 31/7084 (2013.01 - EP); A61K 31/7088 (2013.01 - EP); A61K 31/7105 (2013.01 - EP US); A61K 31/711 (2013.01 - US); A61K 31/713 (2013.01 - EP); A61K 35/763 (2013.01 - EP); A61K 45/06 (2013.01 - EP); A61P 1/00 (2017.12 - US); A61P 37/02 (2017.12 - EP); A61P 37/06 (2017.12 - US); A61P 43/00 (2017.12 - EP); C12N 7/00 (2013.01 - EP); C12N 2710/16632 (2013.01 - EP)
Citation (search report)
- [X] EP 2336317 A1 20110622 - ALNYLAM EUROPE AG [DE]
- [I] WO 2008137901 A2 20081113 - SLOAN KETTERING INST CANCER [US], et al
- [XI] JULIUS CLEMENS FISCHER ET AL: "The Role of the Cytoplasmic RNA Sensor Retinoic Acid Inducible Gene- I (RIG-I) in Allogeneic Stem Cell Transplantation", BLOOD, vol. 124, no. 21, 6 December 2014 (2014-12-06), pages 3827 - 3827, XP055760887, ISSN: 0006-4971, DOI: 10.1182/blood.V124.21.3827.3827
- See references of WO 2018195070A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2018195070 A1 20181025; EP 3612211 A1 20200226; EP 3612211 A4 20210217; US 2020108091 A1 20200409
DOCDB simple family (application)
US 2018027961 W 20180417; EP 18787923 A 20180417; US 201816605883 A 20180417