EP 3635159 A1 20200415 - ENCAPSULATION OF EUKARYOTIC CELLS FOR CELLULAR SCREENING OF EXPRESSED SEQUENCES
Title (en)
ENCAPSULATION OF EUKARYOTIC CELLS FOR CELLULAR SCREENING OF EXPRESSED SEQUENCES
Title (de)
VERKAPSELUNG VON EUKARYONTISCHEN ZELLEN ZUM ZELLULÄREN SCREENING VON EXPRIMIERTEN SEQUENZEN
Title (fr)
ENCAPSULATION DE CELLULES EUCARYOTES POUR LE CRIBLAGE CELLULAIRE DE SÉQUENCES EXPRIMÉES
Publication
Application
Priority
- AU 2017901747 A 20170511
- AU 2018050442 W 20180511
Abstract (en)
[origin: WO2018204986A1] Provided herein are methods for selecting polypeptides or proteins having one or more desired properties from a library of sequences expressed in eukaryotic cells, comprising: encapsulating said cells by photopolymerization; solubilizing said encapsulated cells to produce semipermeable microcapsules; optionally contacting said cells and/or said microcapsules with one or more agents to facilitate detection of activity or function of polypeptides or proteins of interest; and selecting polypeptides or proteins of interest having one or more desired properties. Also provided are methods for encapsulating eukaryotic cells for use in the selection of polypeptides and proteins as described above.
IPC 8 full level
C08F 2/48 (2006.01); C40B 20/00 (2006.01); C40B 30/00 (2006.01)
CPC (source: EP US)
C08F 2/48 (2013.01 - EP); C40B 20/00 (2013.01 - EP US); C40B 30/00 (2013.01 - EP); C40B 30/04 (2013.01 - EP US); C40B 40/02 (2013.01 - EP US); G01N 33/6803 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2018204986 A1 20181115; AU 2018265765 A1 20191205; EP 3635159 A1 20200415; EP 3635159 A4 20210113; JP 2020520455 A 20200709; US 2021054530 A1 20210225; US 2022380936 A1 20221201
DOCDB simple family (application)
AU 2018050442 W 20180511; AU 2018265765 A 20180511; EP 18798855 A 20180511; JP 2019562643 A 20180511; US 201816612132 A 20180511; US 202217818897 A 20220810