EP 3638809 A1 20200422 - NEGATIVE-POSITIVE ENRICHMENT FOR NUCLEIC ACID DETECTION
Title (en)
NEGATIVE-POSITIVE ENRICHMENT FOR NUCLEIC ACID DETECTION
Title (de)
NEGATIV-POSITIVE ANREICHERUNG FÜR DEN NACHWEIS VON NUKLEINSÄUREN
Title (fr)
ENRICHISSEMENT NÉGATIF-POSITIF POUR LA DÉTECTION D'ACIDES NUCLÉIQUES
Publication
Application
Priority
- US 201762519051 P 20170613
- US 201762526091 P 20170628
- US 201762568121 P 20171004
- US 201815877619 A 20180123
- US 201862656592 P 20180412
- US 2018037277 W 20180613
Abstract (en)
[origin: WO2018231945A1] The invention provides methods of detecting a feature of interest in a nucleic acid sample by negatively and positively enriching the sample for segments that contain the feature of interest. Negative enrichment may include digestion of nucleic acids that do not contain the segments, and positive enrichment may include purification of the segments. The methods are useful for diagnostic of genetic elements, e.g., elements indicative of cancer.
IPC 8 full level
C12Q 1/68 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/6848 (2018.01); C12Q 1/6853 (2018.01); C12Q 1/686 (2018.01)
CPC (source: EP)
C12Q 1/68 (2013.01); C12Q 1/6827 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2018231945 A1 20181220; CA 3069934 A1 20181220; CA 3222142 A1 20181220; EP 3638809 A1 20200422; EP 3638809 A4 20210310
DOCDB simple family (application)
US 2018037277 W 20180613; CA 3069934 A 20180613; CA 3222142 A 20180613; EP 18817717 A 20180613