Global Patent Index - EP 3642329 A4

EP 3642329 A4 20210714 - CELL REPROGRAMMING METHODS FOR PRODUCING CHONDROCYTES

Title (en)

CELL REPROGRAMMING METHODS FOR PRODUCING CHONDROCYTES

Title (de)

ZELLNEUPROGRAMMIERUNGSVERFAHREN ZUR HERSTELLUNG VON CHONDROZYTEN

Title (fr)

MÉTHODES DE REPROGRAMMATION CELLULAIRE POUR PRODUIRE DES CHONDROCYTES

Publication

EP 3642329 A4 20210714 (EN)

Application

EP 18820871 A 20180621

Priority

  • AU 2017902385 A 20170621
  • AU 2018050617 W 20180621

Abstract (en)

[origin: WO2018232459A1] The present invention relates to methods and compositions for reprogramming a source cell to produce a chondrocyte, the method comprising activating or increasing the protein expression of one or more transcription factors, or variants thereof, in the source cell.

IPC 8 full level

C12N 5/071 (2010.01); C12N 5/10 (2006.01)

CPC (source: EP US)

C12N 5/0655 (2013.01 - EP US); A61K 45/06 (2013.01 - US); C12N 2500/12 (2013.01 - EP US); C12N 2501/392 (2013.01 - EP US); C12N 2501/60 (2013.01 - EP US); C12N 2501/999 (2013.01 - EP); C12N 2506/1307 (2013.01 - EP US); C12N 2510/00 (2013.01 - EP US)

Citation (search report)

  • [X] WO 2010071210 A1 20100624 - NEW IND RES ORGANIZATION [JP], et al
  • [X] WO 2013036875 A1 20130314 - SINAI SCHOOL MEDICINE [US], et al
  • [X] WO 2015188020 A1 20151210 - VIVOSCRIPT INC [US]
  • [X] HAN NA YANG ET AL: "Chondrogenesis of mesenchymal stem cells and dedifferentiated chondrocytes by transfection with SOX Trio genes", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 32, no. 30, 24 June 2011 (2011-06-24), pages 7695 - 7704, XP028261597, ISSN: 0142-9612, [retrieved on 20110630], DOI: 10.1016/J.BIOMATERIALS.2011.06.059
  • [X] CARON M.M.J. ET AL: "Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures", OSTEOARTHRITIS AND CARTILAGE, vol. 20, no. 10, 1 October 2012 (2012-10-01), GB, pages 1170 - 1178, XP055779796, ISSN: 1063-4584, DOI: 10.1016/j.joca.2012.06.016
  • [X] A. M. CRAFT ET AL: "Specification of chondrocytes and cartilage tissues from embryonic stem cells", DEVELOPMENT, vol. 140, no. 12, 28 May 2013 (2013-05-28), GB, pages 2597 - 2610, XP055278243, ISSN: 0950-1991, DOI: 10.1242/dev.087890
  • [A] WANG YINGJUN ET AL: "Small molecules and their controlled release that induce the osteogenic/chondrogenic commitment of stem cells", BIOTECHNOLOGY ADVANCES, ELSEVIER PUBLISHING, BARKING, GB, vol. 33, no. 8, 1 September 2015 (2015-09-01), pages 1626 - 1640, XP029328710, ISSN: 0734-9750, DOI: 10.1016/J.BIOTECHADV.2015.08.005
  • See references of WO 2018232459A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2018232459 A1 20181227; AU 2018286655 A1 20200116; BR 112019027313 A2 20200721; CA 3067862 A1 20181227; CN 111108189 A 20200505; EP 3642329 A1 20200429; EP 3642329 A4 20210714; IL 271546 A 20200227; JP 2020524515 A 20200820; SG 11201912803Q A 20200130; US 2020165568 A1 20200528

DOCDB simple family (application)

AU 2018050617 W 20180621; AU 2018286655 A 20180621; BR 112019027313 A 20180621; CA 3067862 A 20180621; CN 201880054425 A 20180621; EP 18820871 A 20180621; IL 27154619 A 20191218; JP 2019571016 A 20180621; SG 11201912803Q A 20180621; US 201816625064 A 20180621