EP 3656861 A4 20210407 - ACTIVE MMP9-BINDING PEPTIDE
Title (en)
ACTIVE MMP9-BINDING PEPTIDE
Title (de)
AKTIVES MMP9-BINDENDES PEPTID
Title (fr)
PEPTIDE SE LIANT À LA MMP9 SOUS SA FORME ACTIVE
Publication
Application
Priority
- JP 2017138998 A 20170718
- JP 2018026732 W 20180717
Abstract (en)
[origin: EP3656861A1] The present invention provides a novel peptide that has an amino acid sequence represented by SEQ ID NO: 18, and binds to an active protease but does not bind to a pro-protease.
IPC 8 full level
C12N 15/12 (2006.01); A61K 35/12 (2015.01); A61K 35/76 (2015.01); A61K 38/55 (2006.01); A61K 48/00 (2006.01); A61P 1/04 (2006.01); A61P 1/14 (2006.01); A61P 1/16 (2006.01); A61P 1/18 (2006.01); A61P 3/10 (2006.01); A61P 9/00 (2006.01); A61P 9/04 (2006.01); A61P 9/10 (2006.01); A61P 11/00 (2006.01); A61P 11/02 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 17/00 (2006.01); A61P 17/02 (2006.01); A61P 17/04 (2006.01); A61P 17/06 (2006.01)
CPC (source: EP KR US)
A61K 35/12 (2013.01 - EP KR); A61K 35/76 (2013.01 - EP KR); A61K 38/55 (2013.01 - EP KR); A61K 47/62 (2017.08 - US); A61K 47/68 (2017.08 - US); A61K 48/00 (2013.01 - EP KR); A61P 1/04 (2018.01 - EP KR); A61P 1/14 (2018.01 - EP KR); A61P 1/16 (2018.01 - EP KR); A61P 1/18 (2018.01 - EP KR); A61P 3/10 (2018.01 - EP KR); A61P 9/00 (2018.01 - EP KR); A61P 9/04 (2018.01 - EP KR); A61P 9/10 (2018.01 - EP KR); A61P 11/00 (2018.01 - EP); A61P 11/02 (2018.01 - EP KR); A61P 11/06 (2018.01 - EP KR); A61P 13/12 (2018.01 - EP KR); A61P 17/00 (2018.01 - EP KR); A61P 17/02 (2018.01 - EP KR); A61P 17/04 (2018.01 - EP KR); A61P 17/06 (2018.01 - EP KR); A61P 17/10 (2018.01 - EP KR); A61P 17/14 (2018.01 - EP KR); A61P 19/02 (2018.01 - EP KR); A61P 21/02 (2018.01 - EP KR); A61P 25/00 (2018.01 - EP KR); A61P 25/08 (2018.01 - EP KR); A61P 25/10 (2018.01 - EP KR); A61P 25/14 (2018.01 - EP KR); A61P 25/18 (2018.01 - EP KR); A61P 25/20 (2018.01 - EP KR); A61P 25/22 (2018.01 - EP KR); A61P 25/24 (2018.01 - EP KR); A61P 25/28 (2018.01 - EP KR); A61P 25/30 (2018.01 - EP KR); A61P 25/32 (2018.01 - EP KR); A61P 27/02 (2018.01 - EP KR); A61P 35/00 (2018.01 - EP KR); A61P 37/02 (2018.01 - EP KR); A61P 43/00 (2018.01 - EP KR); C07K 14/001 (2013.01 - US); C07K 14/81 (2013.01 - EP KR); C07K 14/8135 (2013.01 - EP US); C07K 16/38 (2013.01 - EP KR); C12N 5/10 (2013.01 - EP KR); C12P 21/02 (2013.01 - EP KR US); G01N 33/53 (2013.01 - EP KR); G01N 33/68 (2013.01 - US); A61K 38/00 (2013.01 - US)
Citation (search report)
- [X] US 5958699 A 19990928 - BANDMAN OLGA [US], et al
- [T] YANO HIDENORI ET AL: "Discovery of potent and specific inhibitors targeting the active site of MMP-9 from the engineered SPINK2 library", PLOS ONE, vol. 15, no. 12, 29 December 2020 (2020-12-29), pages e0244656, XP055779052, DOI: 10.1371/journal.pone.0244656
- [T] DAISUKE NISHIMIYA ET AL: "A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases", SCIENTIFIC REPORTS, VOL. 9, N.1, 7 August 2019 (2019-08-07), XP055707463, Retrieved from the Internet <URL:http://www.nature.com/articles/s41598-019-47615-5> [retrieved on 20200622], DOI: 10.1038/s41598-019-47615-5
- See also references of WO 2019017338A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3656861 A1 20200527; EP 3656861 A4 20210407; CN 111051339 A 20200421; JP 2022163043 A 20221025; JP 7109440 B2 20220729; JP 7401608 B2 20231219; JP WO2019017338 A1 20200528; KR 102657653 B1 20240416; KR 20200030059 A 20200319; TW 201908337 A 20190301; US 11926655 B2 20240312; US 12043658 B2 20240723; US 2020231654 A1 20200723; US 2023203132 A1 20230629; WO 2019017338 A1 20190124
DOCDB simple family (application)
EP 18836005 A 20180717; CN 201880047818 A 20180717; JP 2018026732 W 20180717; JP 2019531038 A 20180717; JP 2022114824 A 20220719; KR 20207001428 A 20180717; TW 107124740 A 20180718; US 201816631394 A 20180717; US 202218057480 A 20221121