EP 3661937 B1 20210728 - CRYSTALLINE FORMS OF ETHYL ((S)-((((2R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-FLUORO-2,5-DIHYDROFURAN-2-YL)OXY)METHYL)(PHENOXY)PHOSPHORYL)-L-ALANINATE (GS-9131) FOR TREATING VIRAL INFECTIONS
Title (en)
CRYSTALLINE FORMS OF ETHYL ((S)-((((2R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-FLUORO-2,5-DIHYDROFURAN-2-YL)OXY)METHYL)(PHENOXY)PHOSPHORYL)-L-ALANINATE (GS-9131) FOR TREATING VIRAL INFECTIONS
Title (de)
KRISTALLINE FORMEN VON ETHYL ((S)-((((2R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-FLUORO-2,5-DIHYDROFURAN-2-YL)OXY)METHYL)(PHENOXY)PHOSPHORYL)-L-ALANINAT (GS-9131) ZUR BEHANDLUNG VON VIRALEN INFEKTIONEN
Title (fr)
FORMES CRYSTALLINES D'ÉTHYL ((S)-((((2R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-FLUORO-2,5-DIHYDROFURAN-2-YL)OXY)MÉTHYL)(PHÉNOXY)PHOSPHORYL)-L-ALANINATE (GS-9131) POUR LE TRAITEMENT DES INFECTIONS VIRALES
Publication
Application
Priority
- US 201762539822 P 20170801
- US 2018044415 W 20180730
Abstract (en)
[origin: US2019040092A1] The present invention relates to novel forms of ethyl ((S)-((((2R,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate, pharmaceutical formulations, and therapeutic uses thereof in treating viral infections (e.g., an HIV infection).
IPC 8 full level
C07D 473/34 (2006.01); A61K 31/5365 (2006.01); A61K 31/5377 (2006.01); A61K 31/635 (2006.01); A61K 31/675 (2006.01); A61P 31/18 (2006.01); C07D 417/12 (2006.01); C07D 493/04 (2006.01); C07D 498/14 (2006.01); C07H 19/16 (2006.01); C07H 19/20 (2006.01)
CPC (source: EP US)
A61K 31/5365 (2013.01 - EP US); A61K 31/5377 (2013.01 - EP US); A61K 31/635 (2013.01 - EP US); A61K 31/675 (2013.01 - EP US); A61K 45/06 (2013.01 - US); A61P 31/18 (2018.01 - EP US); C07D 417/12 (2013.01 - EP US); C07D 473/34 (2013.01 - EP US); C07D 493/04 (2013.01 - EP US); C07D 498/14 (2013.01 - EP US); C07F 9/65616 (2013.01 - US); C07H 19/16 (2013.01 - EP US); C07H 19/20 (2013.01 - EP US); C07B 2200/13 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 10851125 B2 20201201; US 2019040092 A1 20190207; AR 112642 A1 20191120; EP 3661937 A1 20200610; EP 3661937 B1 20210728; EP 3960740 A1 20220302; EP 3960740 B1 20231115; EP 3960740 C0 20231115; ES 2892402 T3 20220204; ES 2969496 T3 20240520; PL 3661937 T3 20211220; PT 3661937 T 20210924; SI 3661937 T1 20211130; TW 201918250 A 20190516; WO 2019027920 A1 20190207
DOCDB simple family (application)
US 201816049441 A 20180730; AR P180102174 A 20180801; EP 18755368 A 20180730; EP 21186643 A 20180730; ES 18755368 T 20180730; ES 21186643 T 20180730; PL 18755368 T 20180730; PT 18755368 T 20180730; SI 201830414 T 20180730; TW 107126544 A 20180731; US 2018044415 W 20180730