EP 3672582 A4 20210505 - COMPOSITIONS AND METHODS FOR TREATING CANCER
Title (en)
COMPOSITIONS AND METHODS FOR TREATING CANCER
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON KREBS
Title (fr)
COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT DU CANCER
Publication
Application
Priority
- US 201762548879 P 20170822
- US 2018047569 W 20180822
Abstract (en)
[origin: WO2019040647A1] Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in subjects in need thereof. The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in the subject.
IPC 8 full level
A61K 31/165 (2006.01); A61K 31/18 (2006.01); A61K 31/416 (2006.01); A61K 31/4184 (2006.01); A61K 31/45 (2006.01); C12Q 1/68 (2018.01)
CPC (source: EP US)
A61K 31/165 (2013.01 - EP US); A61K 31/343 (2013.01 - US); A61K 31/381 (2013.01 - US); A61K 31/397 (2013.01 - US); A61K 31/416 (2013.01 - EP US); A61K 31/4164 (2013.01 - US); A61K 31/4184 (2013.01 - EP); A61K 31/445 (2013.01 - US); A61K 31/45 (2013.01 - EP); A61K 45/06 (2013.01 - EP); A61K 45/06 (2013.01 - US)
Citation (search report)
- [A] US 6048877 A 20000411 - AHMAD SALEEM [US], et al
- [XI] RYBKA MARTYNA ET AL: "Predictive QSAR study of chalcone derivatives cytotoxicity activity against HT-29 human colon adenocarcinoma cell lines", CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 132, 22 December 2013 (2013-12-22), pages 18 - 29, XP028628294, ISSN: 0169-7439, DOI: 10.1016/J.CHEMOLAB.2013.12.005
- [A] CARVALHO REJANE HUGHES ET AL: "Genomewide DNA Methylation Analysis Identifies Novel Methylated Genes in Non-Small-Cell Lung Carcinomas", JOURNAL OF THORACIC ONCOLOGY, vol. 8, no. 5, 1 May 2013 (2013-05-01), US, pages 562 - 573, XP055789431, ISSN: 1556-0864, DOI: 10.1097/JTO.0b013e3182863ed2
- See also references of WO 2019040647A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2019040647 A1 20190228; AU 2018321950 A1 20200319; CA 3073669 A1 20190228; CN 111182894 A 20200519; EP 3672582 A1 20200701; EP 3672582 A4 20210505; IL 272782 A 20200430; JP 2020531495 A 20201105; JP 7293194 B2 20230619; US 11529338 B2 20221220; US 2020188373 A1 20200618
DOCDB simple family (application)
US 2018047569 W 20180822; AU 2018321950 A 20180822; CA 3073669 A 20180822; CN 201880061797 A 20180822; EP 18848878 A 20180822; IL 27278220 A 20200219; JP 2020510543 A 20180822; US 201816640902 A 20180822