EP 3672623 A1 20200701 - [6R]-MTHF AN EFFICIENT FOLATE ALTERNATIVE IN 5-FLUOROURACIL BASED CHEMOTHERAPY
Title (en)
[6R]-MTHF AN EFFICIENT FOLATE ALTERNATIVE IN 5-FLUOROURACIL BASED CHEMOTHERAPY
Title (de)
[6R]-MTHF EINE EFFIZIENTE FOLATALTERNATIVE IN DER 5-FLUORURACIL-BASIERTEN CHEMOTHERAPIE
Title (fr)
[6R]-MTHF - ALTERNATIVE EFFICACE AU FOLATE DANS LA CHIMIOTHÉRAPIE À BASE DE 5-FLUOROURACILE
Publication
Application
Priority
- EP 17187684 A 20170824
- EP 2018050273 W 20180105
Abstract (en)
[origin: EP3446704A1] The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy.
IPC 8 full level
A61K 39/00 (2006.01); A61K 31/4745 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP IL KR RU US)
A61K 9/0019 (2013.01 - IL US); A61K 31/282 (2013.01 - EP IL US); A61K 31/4545 (2013.01 - EP IL US); A61K 31/4745 (2013.01 - EP IL RU US); A61K 31/513 (2013.01 - EP IL KR RU US); A61K 31/519 (2013.01 - EP IL RU US); A61K 31/525 (2013.01 - KR); A61K 31/555 (2013.01 - EP IL US); A61K 39/00 (2013.01 - RU); A61K 39/395 (2013.01 - EP IL US); A61K 39/39558 (2013.01 - IL US); A61P 35/00 (2018.01 - EP IL KR RU US); C07K 16/22 (2013.01 - IL); A61K 2039/505 (2013.01 - IL US); A61K 2039/545 (2013.01 - IL US); A61K 2300/00 (2013.01 - IL); C07K 16/22 (2013.01 - EP US)
C-Set (source: EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 3446704 A1 20190227; AU 2018320069 A1 20200305; BR 112020003585 A2 20200901; CA 2991357 A1 20190224; CA 3073555 A1 20190228; CA 3073555 C 20230110; CN 110290802 A 20190927; DK 3446705 T3 20211213; EP 3446705 A1 20190227; EP 3446705 B1 20210922; EP 3672623 A1 20200701; ES 2901621 T3 20220323; HU E057332 T2 20220528; IL 272874 A 20200430; IL 272874 B1 20231201; IL 272874 B2 20240401; JP 2019038797 A 20190314; JP 2020531490 A 20201105; JP 7356411 B2 20231004; KR 102216031 B1 20210216; KR 20190022270 A 20190306; MX 2020002053 A 20201211; PL 3446705 T3 20220523; PT 3446705 T 20211229; RU 2020109130 A 20210924; RU 2020109130 A3 20210924; RU 2763934 C2 20220111; SG 10201800195X A 20190328; SG 11202001372T A 20200330; TW 201912159 A 20190401; TW I752147 B 20220111; US 11013744 B2 20210525; US 2019060316 A1 20190228; US 2021401842 A1 20211230; WO 2019037898 A1 20190228
DOCDB simple family (application)
EP 17187684 A 20170824; AU 2018320069 A 20180105; BR 112020003585 A 20180105; CA 2991357 A 20180109; CA 3073555 A 20180105; CN 201880008885 A 20180105; DK 18150455 T 20180105; EP 18150455 A 20180105; EP 18700857 A 20180105; EP 2018050273 W 20180105; ES 18150455 T 20180105; HU E18150455 A 20180105; IL 27287420 A 20200224; JP 2018021069 A 20180208; JP 2020510518 A 20180105; KR 20180002962 A 20180109; MX 2020002053 A 20180105; PL 18150455 T 20180105; PT 18150455 T 20180105; RU 2020109130 A 20180105; SG 10201800195X A 20180109; SG 11202001372T A 20180105; TW 107100834 A 20180109; US 201815865870 A 20180109; US 202117329075 A 20210524