Global Patent Index - EP 3687551 A4

EP 3687551 A4 20210623 - FLUORO SUBSTITUTED PORPHYRIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME

Title (en)

FLUORO SUBSTITUTED PORPHYRIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME

Title (de)

FLUORSUBSTITUIERTE PORPHYRINVERBINDUNGEN, DIESE ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN UND VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG

Title (fr)

COMPOSÉS DE PORPHYRINE FLUOROSUBSTITUÉ, COMPOSITIONS LES COMPRENANT ET PROCÉDÉS DE PRÉPARATION ET D'UTILISATION ASSOCIÉS

Publication

EP 3687551 A4 20210623 (EN)

Application

EP 18861582 A 20180926

Priority

  • US 201762565436 P 20170929
  • US 2018052826 W 20180926

Abstract (en)

[origin: WO2019067523A1] Provided herein are fluoro-substituted porphyrin compounds, such as those having a structure represented by Formula (I), wherein R1 is a C1-C8 alkyl that is substituted with at least 1 fluorine (e.g., a C1-C8 alkyl substituted with 1-17 fluorine atoms); and X is an anion (e.g. a halogen ion (e.g., chloride, etc.), PF6, tosylate, besylate, and/or mesylate). Also provided herein are methods of making the fluoro-substituted porphyrin compounds, pharmaceutical formulations containing the same, and methods of use thereof.

IPC 8 full level

A61K 33/32 (2006.01); A61K 31/409 (2006.01); A61K 31/555 (2006.01); A61P 35/00 (2006.01); C07D 487/22 (2006.01); C07F 13/00 (2006.01)

CPC (source: EP KR US)

A61K 31/375 (2013.01 - EP KR US); A61K 31/409 (2013.01 - EP KR); A61K 31/555 (2013.01 - EP KR); A61K 33/32 (2013.01 - EP KR US); A61K 45/06 (2013.01 - EP KR); A61P 13/08 (2018.01 - KR); A61P 21/00 (2018.01 - KR); A61P 35/00 (2018.01 - EP US); A61P 39/00 (2018.01 - US); C07D 487/22 (2013.01 - EP KR); C07F 13/00 (2013.01 - KR); C07F 13/005 (2013.01 - US); A61N 2005/1094 (2013.01 - EP)

C-Set (source: EP)

  1. A61K 31/375 + A61K 2300/00
  2. A61K 31/555 + A61K 2300/00
  3. A61K 33/32 + A61K 2300/00
  4. A61K 31/409 + A61K 2300/00

Citation (search report)

  • [ID] WO 2010080881 A1 20100715 - UNIV DUKE [US], et al
  • [A] GAUTER-FLECKENSTEIN B ET AL: "Early and late administration of MnTE-2-PyP^5^+ in mitigation and treatment of radiation-induced lung damage", FREE RADICAL BIOLOGY & MEDICINE, ELSEVIER INC, US, vol. 48, no. 8, 15 April 2010 (2010-04-15), pages 1034 - 1043, XP026960987, ISSN: 0891-5849, [retrieved on 20100311]
  • See also references of WO 2019067523A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2019067523 A1 20190404; CA 3076008 A1 20190404; CN 111417400 A 20200714; CN 111417400 B 20221202; EP 3687551 A1 20200805; EP 3687551 A4 20210623; JP 2020536055 A 20201210; JP 7336805 B2 20230901; KR 20200079237 A 20200702; MX 2020002958 A 20200820; US 11344574 B2 20220531; US 2021361702 A1 20211125

DOCDB simple family (application)

US 2018052826 W 20180926; CA 3076008 A 20180926; CN 201880077161 A 20180926; EP 18861582 A 20180926; JP 2020517334 A 20180926; KR 20207010074 A 20180926; MX 2020002958 A 20180926; US 201816645907 A 20180926