EP 3710448 A1 20200923 - MACROCYCLIC CHLORINE SUBSTITUTED INDOLE DERIVATIVES
Title (en)
MACROCYCLIC CHLORINE SUBSTITUTED INDOLE DERIVATIVES
Title (de)
MAKROCYCLISCHE CHLORSUBSTITUIERTE INDOLDERIVATE
Title (fr)
DÉRIVÉS D'INDOLE SUBSTITUÉS PAR DU CHLORE MACROCYCLIQUE
Publication
Application
Priority
- US 201762587925 P 20171117
- EP 2018081370 W 20181115
Abstract (en)
[origin: WO2019096905A1] The present invention relates to macrocyclic indole derivatives of general formula (I) : (I), in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active 10 ingredients.
IPC 8 full level
C07D 487/14 (2006.01); A61K 31/4162 (2006.01); A61P 35/00 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 498/14 (2006.01); C07D 498/20 (2006.01)
CPC (source: EP US)
A61K 31/4162 (2013.01 - EP US); A61K 31/496 (2013.01 - US); A61K 31/5377 (2013.01 - US); A61K 45/06 (2013.01 - US); A61P 35/00 (2017.12 - EP US); C07D 487/04 (2013.01 - EP); C07D 487/14 (2013.01 - EP); C07D 487/18 (2013.01 - US); C07D 498/04 (2013.01 - EP); C07D 498/14 (2013.01 - EP); C07D 498/18 (2013.01 - US); C07D 498/20 (2013.01 - EP)
Citation (search report)
See references of WO 2019096905A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2019096905 A1 20190523; AR 113887 A1 20200624; EP 3710448 A1 20200923; TW 201932469 A 20190816; US 11478451 B1 20221025; UY 37972 A 20190628
DOCDB simple family (application)
EP 2018081370 W 20181115; AR P180103352 A 20181115; EP 18808247 A 20181115; TW 107140664 A 20181115; US 201816764565 A 20181115; UY 37972 A 20181115